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KATE'S BIO
Kate Rubins received her B.S. in Molecular Biology from the University of California, San Diego, where she studied in the Infectious Diseases Laboratory at the Salk Institute for Biological Studies under Dr. Frederic Bushman. Dr. Rubins worked on the mechanism of HIV integration, including several studies of HIV-1 Integrase inhibitors, and genome-wide analyses of HIV integration patterns into host genomic DNA. During her graduate studies at Stanford University, Rubins was part of the research team that developed the first animal model of human smallpox. Since smallpox only infects people, historically there has been no way to study it other than in a Petri dish. As a result, no one has been able to analyze how the virus interacts with the host organism. However, working with the U.S. Army Medical Research Institute of Infectious Diseases and the Centers for Disease Control and Prevention, Rubins and her colleagues succeeded in creating an animal model in the primate Cynomolgus macaques, publishing their results in 2004 in companion papers in the journal Proceedings of the National Academy of Sciences (PNAS). Rubins obtained her PhD from Stanford University, conducting research jointly in the labs of Dr. Patrick Brown and Dr. David Relman, where she was awarded a National Science Foundation Fellowship and a Gabilan Stanford Graduate Fellowship. She also developed a complete map of the poxvirus transcriptome, and studied virus-host interactions using both in vitro and animal model systems. Dr. Rubins is currently a Fellow/Principal Investigator at the Whitehead Institute for Biomedical Research (MIT/Cambridge, MA). Work in the Rubins lab focuses on using poxviruses virus as a tool to explore host-pathogen interaction, as well as to probe mechanisms for regulating host cell mRNA transcription, translation and decay. News stories Early trigger for type-1 diabetes found in mice, Stanford scientists report New Whitehead Fellow Kate Rubins studies infectious disease Stanford scientists help bring study of smallpox virus into ‘molecular age’ Battle for brains: To attract top students, biotech firms turn academic |
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Email : rubins at wi.mit.edu |
Tel : 617.324.4354 |
