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| Monday, March 28, 2011
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Noon - 1:00 PM
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Noon - 1:00 PM
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4:00 PM - 5:00 PM
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| Tuesday, March 29, 2011
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12:30 PM - 1:30 PM
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1:00 PM - 4:30 PM
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Biosensors Nanocourse
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| Description: |
Course Lecturers: Jessica Tytell (HMS Cell Biology), Gary Yellen (HMS Neurobiology), Barbara Imperiali (MIT Dept. of Chemistry)
Location: Harvard Medical School Quad, Goldenson Building, Room 122
https://nanosandquarters.hms.harvard.edu/node/149
The goal of this course is to introduce the design principles and applications of fluorescence-based biosensors in cell biology. First, an overview of biosensors will be given to introduce general concepts and usage of fluorescent-protein based systems and environment sensitive dye-based systems. The second lecture will describe the design, execution and analysis of a protein-based biosensor. The third lecture will introduce different chemistries and design strategies for environmentally-sensitive chemical probes and dyes. The combination of these lectures is designed to introduce students to the basic types of biosensors and insight into their design. This nanocourse is meant to be a broad introduction to the concepts of biosensor design and application and to encourage students to think about the ways in which biosensors can be utilized to ask deeper questions about their research. It is not intended to serve as a technical introduction to biosensor work and therefore, although we will cover the need for controls and what types of controls should be done in various cases, we do not intend to give extensive technical detail about imaging conditions or analysis methods.
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| Contact: |
Ondra Kielbasa
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4:00 PM - 5:00 PM
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| Wednesday, March 30, 2011
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11:30 AM - 1:00 PM
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Noon - 1:00 PM
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2:00 PM - 3:20 PM
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Glial Modulators: Potential new treatments for chronic pain or brain tumors?
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| Description: |
Joyce A. DeLeo, Ph.D., Professor and Chair of Pharmacology and Toxicology, Dartmouth Medical School, Hanover, NH. Boston University School of Medicine, 72 East Concord Street, L-112, Boston, MA. Part of the Current Topics in Pharmacological Sciences Seminar Series sponsored by the Department of Pharmacology & Experimental Therapeutics. Free and open to the public. Refreshments served at 1:45 pm, R-Building 6th Floor.
www.bumc.bu.edu/busm-pm
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| Contact: |
Kristina Bigdeli
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4:00 PM - 5:00 PM
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5:00 PM - 6:00 PM
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| Thursday, March 31, 2011
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4:00 PM - 5:00 PM
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More Than One Way to Kill a Brain Tumor Cell
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| Description: |
Tufts University Program in Cell, Molecular and Developmental Biology Seminar Series
Guest Speaker: Joseph Verdi, PhD, Maine Medical Center Research Institute
Location: Tufts University, Sackler School of Graduate Biomedical Sciences, Sackler Auditorium, 145 Harrison Avenue, Boston
There will be a wine and cheese reception immediately following the seminar in the M&V Building 5th floor library, 136 Harrison Avenue, Boston
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| Contact: |
Sharon Titus
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4:00 PM - 5:30 PM
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The Hans Lukas Teuber Lecture: The Basal Ganglia: Binding Values to Action
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| Description: |
2011 MIT Colloquium on Brain and Cognition:
The Hans-Lukas Teuber Lecture
Speaker: Ann M. Graybiel, MIT, Department of Brain and Cognitive Sciences, McGovern Institute for Brain Research
Place: MIT, Singleton Auditorium, 46-3002
Title: The Basal Ganglia: Binding Values to Action
Abstract:
Our lives are filled with action. Though we usually think of cortical circuits as controlling what we do, experimental and clinical evidence now suggests that much of what we do is guided by deep brain structures including the basal ganglia. We are probing these basal-ganglia circuits in order to find out how they change as we learn new habits and routines. This lecture will summarize work suggesting that cortico-basal ganglia pathways can exhibit high levels of flexibility related to behavioral change, but that their activity can also become overly fixed despite the need for change. This interplay between flexibility and fixity may underlie dysfunctions of these circuits leading to motor and neuropsychiatric problems in basal ganglia-based disorders.
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| Contact: |
Kathleen Dickey
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4:30 PM - 5:30 PM
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7:00 PM - 9:00 PM
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Making Synthetic Biologists - iGEM the International Genetically Engineered Machine Competition
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| Description: |
Can simple biological systems be built from standard, interchangeable parts and operated in living cells? OR, is biology so complicated that every case is unique? The minicomputer revolution thrived on interchangeable parts from the TTL catalogue. There was a rich explosion in computer companies, semiconductor companies, and the industries that supported and used those computers. Today, the biotechnology industries are like the mainframe companies of the 1960's. Can the engineering principles of standardization and interchangeable parts create an industrial revolution of synthetic biology based on standard parts? iGEM, the International Genetically Engineered Machine Competition is implementing this vision. Each year teams of undergraduate students are given a kit of 1000 biological parts as DNA. The parts include sensors for small molecules, coding regions for various proteins, and other control parts. Over the summer, the teams build systems from these parts and make new parts of their own. They come together at MIT in the fall, present their work, win prizes, and have fun meeting other new synthetic biologists.
Randy Rettberg is the Founder and Director of iGEM at MIT. Previously, he worked as a computer and network designer at BBN, Apple, and Sun.
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| Contact: |
Peter Mager
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| Friday, April 1, 2011
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8:30 AM - 9:30 AM
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Upper respiratory tract microbiota and pathogen carriage
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| Description: |
Speaker: Katherine Lemon, Forsyth Institute
Location: Harvard University Center for the Environment (HUCE), 24 Oxford St, 3rd Floor, Room 310
Notes: MSI Weekly Chalktalk! Please join us for coffee/tea/pastries at 8:30 AM, followed by the chalktalk at 8:45.
http://www.msi.harvard.edu/fridays.html
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| Contact: |
Andrea Lenco
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1:25 PM - 2:45 PM
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Week of Sunday, March 27, 2011
