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| Monday, March 14, 2011
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Noon - 1:00 PM
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Antibiotics for all? Current recommendations and recent findings
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| Description: |
Location: The Forsyth Institute, Seminar Room A
245 First St., 17th Floor, Cambridge
Speaker: Andrea Mombelli, Prof. Dr.med.dent.
Professor and Head, Division of Periodontology
Associate Vice-Dean, Faculty of Medicine
University of Geneva, School of Dental Medicine
Summary: Beneficial effects of systemic antibiotics for patients with periodontal diseases have been demonstrated multiple times. Although these advantages are clear in general, the specific relationship of benefit and risk in various clinical situations remains a subject of debate. Uncertainties persist regarding the individual prescription and combination with other procedures. It has been pointed out that systemic antibiotics given in the context of non-surgical sub-gingival debridement may reduce the need for periodontal surgery. Recent studies confirm these findings especially with regards to the combination of amoxicillin and metronidazole. This presentation will address various paradigms and questions in the context of antimicrobial treatment of periodontal diseases. A treatment protocol implementing the recent evidence will be shown.
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| Contact: |
Pam Quattrocchi
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4:00 PM - 5:00 PM
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| Tuesday, March 15, 2011
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12:30 PM - 1:30 PM
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4:00 PM - 5:00 PM
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| Wednesday, March 16, 2011
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11:30 AM - 1:00 PM
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Bioinformatics Seminar Series: Information from Networks
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| Description: |
Speaker: Leonid Chindelevitch, Pfizer.
MIT's Stata Center TOC Lab Building 32-G575.
The networks describing the interaction between different biological entities can yield a lot of interesting information if analyzed properly. This talk will describe the analysis of two kinds of networks: metabolic networks and causal regulatory networks. We will construct mathematical models to ask questions of each kind of network, describe the algorithms required to provide answers, and finally discuss the kind of biological insights that arise from this analysis.
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| Contact: |
Patrice Macaluso
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4:00 PM - 5:00 PM
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Neuroscience Seminar - David Brody
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| Description: |
Neuroscience Seminar:
David Brody, Washington University in St Louis
Title of Talk: "Amyloid-beta Dynamics Following Traumatic Brain Injury- Human Studies and Experimental Models"
Location:
Jaharis 508
150 Harrison Avenue
Boston, MA 02111
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| Contact: |
Laila Lee
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6:00 PM - 7:30 PM
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| Thursday, March 17, 2011
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4:00 PM - 5:00 PM
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Growth Regulatory Pathways in Drosophila Intestinal Stem Cell-Mediated Regeneration
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| Description: |
Tufts University Program in Cell, Molecular and Developmental Biology Seminar Series
Guest Speaker: Tony Ip, PhD, Associate Professor in Molecular Medicine at the University of Massachusetts Medical School
Location: Tufts University Sackler School of Graduate Biomedical Sciences, Sackler Auditorium, 145 Harrison Avenue, Boston, MA 02111
There will be a wine and cheese reception immediately following the seminar in the M&V Building 5th floor library, 136 Harrison Avenue, Boston
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| Contact: |
Sharon Titus
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4:00 PM - 5:30 PM
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MIT Colloquium on the Brain and Cognition: The self-tuning neuron: homeostatic synaptic scaling of excitatory synapses
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| Description: |
Gina Turrigiano, Brandeis University
Room 3002, Singleton Auditorium, Building 46, MIT
Abstract:
The positive-feedback nature of Hebbian synaptic plasticity can destabilize the properties of neuronal networks. Recent work from my lab and others has suggested that this destabilizing influence is counteracted by homeostatic plasticity mechanisms that stabilize neuronal activity. One such mechanism, homeostatic synaptic scaling, is a form of synaptic plasticity that adjusts the strength of all of a neuron's excitatory synapses up or down to stabilize firing. Here I will discuss our recent work showing synaptic scaling is a cell-autonomous process in which neurons detect changes in their own firing rates through a set of calcium-dependent sensors that then regulate receptor trafficking to increase or decrease the accumulation of glutamate receptors at synaptic sites. I will discuss the signaling pathways that underlie this process, the biophysical changes at synapses that allow synaptic strength to be scaled up or down, and (time permitting) the role this plasticity plays in experience-dependent development of the visual system.
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| Contact: |
Keren Miller
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4:30 PM - 5:30 PM
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| Friday, March 18, 2011
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8:30 AM - 9:30 AM
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Week of Sunday, March 13, 2011
