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Monday, October 25, 2010 Noon - 1:00 PM Biomolecular Seminar Series: Endocytosis-Mediated Cell Death in Drosophila Photoreceptors Description: A talk by Dr. Patrick Dolph, Dartmouth College LSE B01, Boston University, 24 Cummington Street, Boston, MA 02215 http://people.bu.edu/celenza/Biomolecular.html Contact: Dr. John Celenza Noon - 1:30 PM Proteomic analysis of blastema formation in regeneration-competent vs. regeneration-deficient amphibian limbs Description: Speaker: Dr. David Stocum (Indiana Universit/Purdue University Indianapolis, IUPUI) Location: 90 Snell Library, Northeastern University, 360 Huntington Avenue, Boston Hosted by: Gunther Zupanc Contact: Laura McGann 4:00 PM - 5:00 PM The enzymatic activity of sirtuins: Beyond NAD-dependent deacetylation Description: Biochemistry Seminar Series Speaker: Professor Hening Lin, Cornell University Room 114, Building 56, MIT Contact: Betty Lou McClanahan Tuesday, October 26, 2010 12:30 PM - 1:30 PM The Yin and Yang of Chemical Signaling in Bacterial-Host Associations Description: Speaker: Vanessa Sperandio, UT Southwestern Medical Center Location: Harvard Med School, Warren Alpert Bldg, Room 341 Host: Dr. Michael Starnbach Coffee and snacks served at 12:15 PM outside the room Contact: Shannon Humphreys 4:00 PM - 5:00 PM Seminars in Oncology: How Not to Get Fired: Regulation of Origin Use After DNA Damage Description: Guest Speaker: David Toczyski, University of California - San Francisco,br> Location: Jimmy Fund Auditorium, Dana-Farber Cancer Institute Host: David Pellman, 617-582-7646 http://www.dfhcc.harvard.edu/news/announcements/article/3783/322/?PHPSESSID=26103a2246b7e0fb0311565fe2e3f081 Contact: Claudia Steele 4:00 PM - 5:00 PM Transcriptional Control of Cardiovascular Development Description: Cardiovascular Seminar Series Speaker: Brian Black, University of California, San Francisco Location: Folkman (Enders) Auditorium, John F. Enders Research Bldg., Children's Hospital Boston This conference is supported by the Faye and Karen Sinclair Research Fund for Congenital Heart Disease Contact: Michelle Merry Thursday, October 28, 2010 Noon - 1:15 PM Host Nutrition and the Ecology of Infectious Diseases Description: Speaker: Dr. Val H. Smith, University of Kansas Location: The Forsyth Institute, 245 First Street, 17th Floor, Cambridge Contact: Pam Quattrocchi 4:00 PM - 5:30 PM MIT Colloquium on the Brain and Cognition: Toward a single-trial view of motor preparation Description: Speaker: Krishna Shenoy, Stanford University Location: Room 3002, Bldg 46, The Singleton Auditorium, MIT Abstract: Our seemingly effortless ability to reach out and swat a fly or grab a cup belies the sophisticated neural computations at work in our nervous system. It has long been recognized that, before moving, we somehow prepare neural activity such that, when called upon, the desired movement unfolds. But the goals of movement preparation and the underlying neural mechanisms remain poorly understood. I will describe some of our recent electrophysiological investigations of how premotor cortex prepares and helps execute movements. Our results suggest that the brain is attempting to optimize preparatory neural activity and can delay movement until this activity is sufficiently accurate. We note that the spiking activity during motor preparation exhibits dynamics beyond that driven by external stimulation, presumably reflecting the extensive recurrence of neural circuitry. We have been developing analysis methods for capturing the dynamics from (96 channel) simultaneous PMd neural recordings while monkeys perform delayed reaching tasks, and I will present recent work that examines the trial-by-trial neural trajectories during movement preparation and generation and their relationship with behavior. Characterizing these dynamics may reveal important features of neural computation, and may be useful for further increasing the performance of neural prostheses. Contact: Vivi Hinh 5:30 PM - 6:30 PM Linking the Practice of Medicine to Public Health: The Key to the Success of Health Care Reform Description: The 35th Joseph Garland Lecture sponsored by the Boston Medical Library in the Countway Library of Medicine This year's speaker is John Auerbach, M.D., Commissioner of Public Health, Commonwealth of Massachusetts. Location - Armenise Amphitheatre, Armenise Bldg., Harvard Medical School, 200 Longwood Ave., Boston Contact: Roz Vogel Friday, October 29, 2010 8:30 AM - 9:30 AM Micro-friend or foe? Identity and territorial behavior in Proteus mirabilis Description: Speaker: Karine Gibbs (FAS-MCB) Location: Harvard University Center for the Environment (HUCE), 24 Oxford St, 3rd Floor, Room 310 Notes: MSI Weekly Chalktalk! Please join us for coffee/tea/pastries at 8:30 AM, followed by the chalktalk at 8:45. Contact: Andrea Lenco 1:40 PM - 3:00 PM Boston University School of Medicine Department of Pathology and Laboratory Medicine Fall 2010 Seminar Series Description: Macrophage Response: Analysis in Context Mikael Pittet, Massachusetts General Hospital Gottlieb Conference Room L-804, Instructional Building, Boston University Medical Campus Debbie Kiley/ dekiley@bu.edu Contact: Debra Kiley

Week of Sunday, October 24, 2010

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