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Previous Period  Week of Sunday, April 3, 2011    Next Period 
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Monday, April 4, 2011
Noon - 1:00 PM
Biology Department Seminar
Description: "Forward Planning for good mothering: Epigenetic co-adaptation of brain and placenta"
Dr. E.B. Keverne,FRS, Department of Zoology, University of Cambridge, United Kingdom
24 Cummington Street, LSE B01, Boston University, Boston
Contact: Dr. Chip Celenza
Noon - 1:00 PM
HNRCA Spring Seminar Series with Paul Wade
Description: Join us for a seminar led by Dr. Paul Wade. The topic will be "DNA methylation dynamics during immune cell activation".
Location:
Jean Mayer USDA HNRCA @ Tufts University
711 Washington Street
Mezzanine Conference Room
Boston, MA 02111
The event is held in a government building, with security at the front door. In order to gain admittance you will need to bring a government ID to present at the door.
Contact: Christine O'Connell
4:00 PM - 5:00 PM
MGH Cutaneous Biology Research Center Special Seminar
Description: Elizabeth Grice, National Human Genome Research Institute (NHGRI)
"Genomic Analysis of Skin Microbiota in Health and in Chronic Diabetic Wounds"
MGH East, Building 149, Isselbacher Auditorium 7th Floor Charlestown, MA
Contact: Vivian Theodoracopoulos
Tuesday, April 5, 2011
12:30 PM - 1:30 PM
Metabolic and Signaling Strategies for Maintaining a Long-Term Beneficial Bacteria-Host Association
Description: Speaker: Ned Ruby, University of Wisconsin-Madison
Location: Harvard Med School, Warren Alpert Bldg, Room 341
Host: Microbiology Graduate Students
Coffee and snacks served at 12:15pm outside the room
Contact: Shannon Humphreys
Wednesday, April 6, 2011
Noon - 1:00 PM
Abnormal protein degradation in Huntington's disease
Description: Hyemyung Seo, Hanyang University, South Korea
Seminar is at: Auditorium, Boston Biomedical Research Institute, 64 Grove Street, Watertown
Contact: Moonkyoung Um
Noon - 1:00 PM
Heart Failure and Neurodegenerative Processes: an Unfolding Story
Description: Fyler Lecture
Grand Rounds
Guest Lecturer:
Jeffrey Robbins, Cincinnati Children's Research Foundation
Folkman Auditorium, J.F. Enders Research Bldg., Children's Hospital Boston
Contact: Michelle Merry
2:00 PM - 3:20 PM
Adenosine/Dopamine Interactions Regulating Behavioral Activation and Effort-Related Decision Making: Implications for Psychiatry and Neurology
Description: John Salamone, Ph.D., Professor of Behavioral Neuroscience, and Neuroscience, Department of Psychology, Storrs, CT. Boston University School of Medicine, 72 East Concord Street, L-112, Boston, MA. Part of the Current Topics in Pharmacological Sciences Seminar Series sponsored by the Department of Pharmacology & Experimental Therapeutics. Free and open to the public. Refreshments served at 1:45 pm, R-Building 6th Floor.

www.bumc.bu.edu/busm-pm
Contact: Kristina Bigdeli
4:00 PM - 5:00 PM
Neuroscience Seminar - Nathan Schoppa
Description: Tufts University Neuroscience Seminar
Nathan Schoppa, University of Colorado
Title of Talk: "Neural circuitry between sensory input and output mitral cells in the olfactory bulb"
Location: Jaharis 508, 150 Harrison Avenue, Boston, MA 02111
Handicap Accessible
Contact: Laila Lee
6:00 PM - 7:30 PM
Importance of autism as a neurologic disorder: Implications for understanding cause and for intervention
Description: Nancy J. Minshew, MD Professor of Psychiatry and Neurology, University of Pittsburgh School of Medicine Please RSVP to lmavros@mit.edu if you'd like to attend. You can find more information on this talk, including an abstract, at web.mit.edu/autism. Supported by the Simons Initiative on Autism and the Brain at MIT (web.mit.edu/autism)
Contact: Lee Mavros Rushton
6:00 PM - 8:30 PM
Plants in New England (PINE)
Description: Plants in New England
When: Wednesday April 6, 2011, 6 pm.
Where: Whitehead Institute McGovern Auditorium
http://www.wi.mit.edu/about/directions.html Speakers:
Kirsten Bomblies, (Harvard University)
Sebastian Marquardt (Buratowski Lab, HMS)
Matthew Ramon (Sheen Lab, MGH)
Contact: chip celenza
Thursday, April 7, 2011
11:00 AM - Noon
Evolutionary Biology Lecture Series: Pardis Sabeti, "Selection in the Human Genome"
Description: Evolutionary Biology Lecture Series
Pardis Sabeti, "Selection in the Human Genome"
MIT, Maclaurin Building, 4-370
Contact: Laura Resteghini
Noon - 1:00 PM
Dark matter transcription revealed by single-molecule sequencing
Description: Speaker: Philipp Kapranov, St. Laurent Institute, Vancouver, WA
Location: The Forsyth Institute, Seminar Room A, 245 First St., 17th Floor, Cambridge
Abstract: Discovery of multiple classes of non-coding RNAs (ncRNAs), both long (>200 nt) and short (<200nt), in many biological systems has transformed our understanding of genome complexity in recent years and suggest new paradigms of genome regulation. However, what fraction of all cellular RNA consists of ncRNAs and what fraction of the genome is utilized to produce them remain controversial. Far more than a bookkeeping issue, the degree to which this so called “dark matter transcription” is present has important implications regarding its biologic function, and the general architecture of genome regulation. In particular, elucidation of how ncRNAs regulate genome function will be compromised if they are dismissed as ‘transcriptional noise’. Single-molecule sequencing (SMS) is an ideal tool to assess and accurately quantify transcriptome complexity of a cell. When applied to the human transcriptome, it revealed that the relative mass of non-coding RNAs as a proportion of all non-ribosomal non-mitochondrial human RNA can be greater than that of protein encoding transcripts and this complexity is lost in polyA-selected RNA. We further show the presence of a large number of very long abundantly-transcribed regions (e.g., 100’s of kb) in the genome’s intergenic space and show that these regions tend to associate with neoplastic transformation and their overlap with ncRNAs previously found in normal human embryonic tissues raises an interesting hypothesis as to function of the former in the early development and neoplastic transformation. The presentation will provide the details of these results and discuss their implications for our understanding of the biology of cell.
Contact: Pam Quattrocchi
Noon - 1:30 PM
Hacking Medicine @ MIT
Description: Hacking Medicine @ MIT Series: Hacking Health Software
Ed Park the Chief Operating Officer of athenahealth will be coming to MIT on April 7th to discuss Hacking Medicine in the context of athenahealth's own hack on the healthcare industry, how they achieved it, and what impact it had. Along with Zen Chu, Entrepreneur in Residence at MIT, they will layout a visual landscape for the Healthcare Industry and discuss the areas that have the highest hackability potential. Ed and Zen will also discuss several case studies of other venture backed businesses to hack medicine and improve healthcare.
What: Ed Park, COO, Athena Health and Zen Chu, Entrepreneur in Residence, MIT
When: April 7th, 2011, 12:00 - 1:30 PM
Where: 32-155 Stata Center @ MIT
Topic: H@cking Medicine to Improve Healthcare
Space is limited, please reserve a seat here: http://entrepreneurship.mit.edu/hacking-medicine-ed-park-coo-athenahealth
Contact: Zen Chu
4:30 PM - 5:30 PM
Vascular Biology Seminar: Notch in Angiogenesis: Arterial Venous Programming in Development & Disease
Description: Rong Wang, University of California San Francisco
Location: Folkman Auditorium, Enders Bldg., Children's Hospital Boston, 320 Longwood Ave.
Contact: David Lynn, 617-525-4351
6:00 PM - 9:00 PM
‘Get on Board: Inside the Board of Directors’ Panel Discussion
Description: If you would like to learn about the impact being on a board has on your career. If you would like to serve on a board, are already on a board, or work with a board, join us for Get on Board. The panelists are directors of both for-profit and nonprofit organization boards, and will address issues relating to service as directors, including the combinations of skills and experiences that boards are seeking, how to best position yourself for a for-profit or nonprofit board candidacy, resources available to help you identify and take advantage of both paid and volunteer board opportunities, what it’s like to serve as a director on a board, and issues particular to women on boards. Speakers include:
• Susan C. Hammond, Principal, scHammond Advisors
• Leslie Meyer-Leon, President, IP Legal Strategies Group, P.C.
• Bob Fischer, Principal, BigVisible Systems, Agile Software Development
• Sandra Glucksmann, Senior VP of Research & Business Operations, Cerulean Pharma
This event is open to the public. Light refreshments are included.
http://www.westorg.org/mc/page.do?sitePageId=125130
Contact: susan silberman
Friday, April 8, 2011
8:30 AM - 9:30 AM
Structure & function in natural microbial communities: a transcriptomic perspective
Description: Speaker: Edward Delong, MIT
Location: Harvard University Center for the Environment (HUCE), 24 Oxford St, 3rd Floor, Room 310
Notes: MSI Weekly Chalktalk! Please join us for coffee/tea/pastries at 8:30 AM, followed by the chalktalk at 8:45.
http://www.msi.harvard.edu/fridays.html
Contact: Andrea Lenco
12:30 PM - 1:30 PM
Transcriptional Networks and Microbiota in the Regulation of Inflammatory T Cells
Description: Dan Voytas, Professor and Director, Center for Genome Engineering, University of Minnesota
Fred S. Rosen Conf. Room, CLSB 3069, Immune Disease Institute, 3 Blackfan Circle
Hosted by: Fred Alt
Contact: Zac DiPasquale
1:30 PM - 2:45 PM
Boston University School of Medicine Pathology and Laboratory Medicine Spring 2011 Seminar Series
Description: Guest Speaker: Paola Arlotta, PhD; Assistant Professor of Surgery, Department of Stem Cell and Regenerative Biology; Harvard Medical School. Talk Title: “Molecular Development of Projection Neuron Types and Building of Local Microcircuitry in the Cerebral Cortex”

Boston University Medical Campus; 670 Albany Street (behind 700 Albany); Lobby Level #107/108
Contact: Debbie Kiley
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