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| Monday, February 25, 2013
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Noon - 1:00 PM
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4:00 PM - 5:00 PM
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4:30 PM - 5:30 PM
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| Tuesday, February 26, 2013
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12:30 PM - 1:30 PM
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4:00 PM - 5:00 PM
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4:00 PM - 5:00 PM
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Seminars in Oncology: "Oncogenic Pathways, Drug Resistance and Targeted Therapies in T-All"
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| Description: |
Guest Speaker: Adolfo Ferrando, MD, PhD, Associate Professor of Pathology and Pediatrics, Columbia University
New York, NY
Location: Jimmy Fund Auditorium, (35 Binney Street - Boston)
Hosted by: William Hahn, MD, PhD, 617-582-7646.
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| Contact: |
Claudia Steele
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| Wednesday, February 27, 2013
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11:30 AM - 1:00 PM
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Bioinformatics Seminar Series:RNA conformational switches and the Fast Fourier Transform
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| Description: |
Peter Clote, Boston College
TOC Lab, MIT's Stata Building 32 Room G575
RNA secondary structure forms a scaffold for tertiary structure formation,
hence is a major determinant for both structure and function of an RNA molecule. While protein secondary structure is predicted by machine learning methods, RNA secondary structure can be predicted by dynamic programming methods that use an ab initio energy model will experimentally measured free energy parameters. Such thermodynamics-based methods constitute important tools especially when confronted with novel RNAs of unknown function.
In this talk, we describe two recent results. First, we briefly describe a new algorithm, RNAsc, to optimally predict RNA secondary structure when integrating chemical/enzymatic probing data, such as in-line probing or SHAPE data (selective 2'-hydroxyl acylation analyzed by primer extension). Secondly, we describe a thermodynamics-based algorithm, FFTbor, for conformational switch prediction that employs the FFT to determine partition functions by polynomial interpolation.
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| Contact: |
Patrice Macaluso
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| Thursday, February 28, 2013
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8:00 AM - 5:00 PM
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Health Equity Symposium: Science & Medicine in Africa
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| Description: |
Date: February 28, 2013
Location: Novartis, 250 Massachusetts Avenue, Auditorium, Cambridge, MA 02144
How do we create a new scenario in which every nation in the developing world has the power to improve the health of its population in the face of challenges?
Attend HES 2013 to learn about new, more effective approaches of increasing science and technology capabilities within the developing world.
Keynote Speaker: Sir Nigel Crisp, Member of the UK House of Lords and former Director of the UK National Health Service
Presentations and panel discussions will address the following topics:
• Scientific capability development as a bidirectional effort.
• What industrialized and developing nations can learn from each other
Two visions: the future of basic science and clinical research in Africa
• An in-depth discussion with the audience on open questions and innovative solutions to infrastructure building and capabilities development
• Emerging challenges – dealing with the rise of chronic diseases in Africa and the developing world
• African genome projects - optimizing treatment for genetically diverse populations
• What lessons can be learned from efforts to eradicate disease?
• Exploring the benefits of healthier nations – an economic dividend
For the full program and to register visit www.healthequitysymposium.com
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| Contact: |
Meghan Somers
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12:15 PM - 1:45 PM
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Systems Biology Seminar
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| Description: |
Hongzhe Li, Professor of Biostatistics in Biostatistics and Epidemiology, University of Pennsylvania
All talks to be held in LSE room 103, Boston University (24 Cummington St., Boston, MA) on Thursdays.
A free lunch will begin at 12:15; talks will begin at 12:45 unless otherwise noted.
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| Contact: |
Paige Fults
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| Friday, March 1, 2013
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8:30 AM - 9:30 AM
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2:00 PM - 3:00 PM
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Week of Sunday, February 24, 2013
