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| Friday, February 1, 2013
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8:30 AM - 9:30 AM
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2:00 PM - 3:00 PM
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| Tuesday, February 5, 2013
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12:30 PM - 1:30 PM
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4:00 PM - 5:00 PM
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| Wednesday, February 6, 2013
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Noon - 1:00 PM
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| Friday, February 8, 2013
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12:30 PM - 1:30 PM
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PCMM Seminar Series
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| Description: |
Cell Biological Aspects of Innate Immunity
Jonathan Kagan, Ph.D.
Fred S. Rosen Conference Room, CLSB, 3 Blackfan Circle – 3rd Floor, Room 3069
Hosted by: Sun Hur, Ph.D.
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| Contact: |
Zac DiPasquale
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| Monday, February 11, 2013
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Noon - 1:00 PM
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Aging and changes in kidney function
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| Description: |
Speaker: Mark Sarnak, Tufts Medical Center
All HNRCA Seminars will be held at 12 noon in the Auditorium of the HNRCA and will be followed by a student and post-doc luncheon on the 9thfloor, 711 Washington St. Boston
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| Contact: |
John Heine
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| Tuesday, February 12, 2013
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12:30 PM - 1:30 PM
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Metabolic Regulation of T Cell Function
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| Description: |
Dr. Erika Pearce, Washington University
New Research Building - Room 1031, Harvard Medical School, 77 Ave. Louis Pasteur
Hosted by Dr. Arlene Sharpe
Refreshments served at 12:15 pm outside the room
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| Contact: |
Jessica Conner
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4:00 PM - 5:00 PM
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| Wednesday, February 13, 2013
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6:00 PM - 9:00 PM
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WEST: Anatomy of a Blindside
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| Description: |
Workshop given by Bonnie Marcus, Executive Coach
The workplace is a highly politicized environment where key decisions about who gets ahead and who gets plum assignments, who gets the scarce resources are not just decided on merit, but politics.
Everyone talks about the glass ceiling and how women need to knock on the glass ceiling to get ahead. What’s really going on is that there is a political power grid that holds women back, not a glass ceiling, and this power grid is so hidden and buried that women don’t even know it exists. And because they don’t know it exists, they can accidentally step on something and get blindsided.
During this presentation, attendees will learn:
How to identify the power grid in their workplace<
How to navigate the power grid and avoid the landmines
How to get ahead and stay ahead in today’s workplace
Location:
The Broad Institute of MIT and Harvard, Monadnock Room
7 Cambridge Center, Cambridge, MA 02142
Cost: Members: $40; Non-Members: $60
A light dinner will be served.
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| Contact: |
Jaime Mayo
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| Thursday, February 14, 2013
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5:30 PM - 7:00 PM
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| Tuesday, February 19, 2013
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12:30 PM - 1:30 PM
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| Thursday, February 21, 2013
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Noon - 1:00 PM
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Single Molecule Arrays (Simoa) for the ultrasensitive detection of proteins and nucleic acids
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| Description: |
Speaker: David C. Duffy, PhD, Vice President, Research, Quanterix Corporation
Location: The Forsyth Institute, Seminar Room A, 245 First Street, Cambridge
Summary:We will describe the single molecule array technology —or Simoa—that allows multiple proteins to be detected at concentrations 1000-fold lower than is possible with current diagnostic technology. The technology has single molecule resolution, and is based on capturing and labeling protein molecules on magnetic beads, and imaging those beads in arrays of thousands of femtoliter wells. The ability to detect proteins at subfemtomolar concentrations enables biomarkers that are discovered using proteomic and genomic strategies to be measured in bodily fluids, and used as clinical diagnostics. We will provide examples of biomarker detection in cancer, neurological disorders, and infectious diseases, highlighting the collaboration with the Forsyth to detect biomarkers from Mycobacterium tuberculosis. A fully automated Simoa instrument, capable of multiplexed biomarker detection will be described, as well as Simoa assays for DNA and RNA.
Educational/Learning Objectives
•The audience will be educated on the fundamentals of an innovative single molecule technology for detecting protein and nucleic acid biomarkers.
•They will hear how the translation of biomarkers from discovery to measurement in the clinic is a major technological challenge facing the development of diagnostics.
•They will hear how more sensitive measurements of proteins in bodily fluids can be applied in cancer, neurology, and infectious diseases.
•They will also be educated on instrumentation used to make single molecule measurements.
_1_ Continuing education credits provided by The Forsyth Institute.*
*The Forsyth Institute is an ADA CERP recognized provider . ADA CERP is a service of the American Dental Association to assist dental professionals in identifying quality providers of continuing dental education. ADA CERP does not approve or endorse individual courses or instructors, nor does it imply acceptance of credit hours by boards of dentistry. Concerns or complaints about a CE provider may be directed to the provider or to ADA CERP at www.ada.org/cerp. The Forsyth Institute designates _1_continuing education credits.
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| Contact: |
Pam Quattrocchi
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| Friday, February 22, 2013
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8:30 AM - 9:30 AM
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| Monday, February 25, 2013
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Noon - 1:00 PM
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4:00 PM - 5:00 PM
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4:30 PM - 5:30 PM
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| Tuesday, February 26, 2013
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12:30 PM - 1:30 PM
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4:00 PM - 5:00 PM
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4:00 PM - 5:00 PM
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Seminars in Oncology: "Oncogenic Pathways, Drug Resistance and Targeted Therapies in T-All"
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| Description: |
Guest Speaker: Adolfo Ferrando, MD, PhD, Associate Professor of Pathology and Pediatrics, Columbia University
New York, NY
Location: Jimmy Fund Auditorium, (35 Binney Street - Boston)
Hosted by: William Hahn, MD, PhD, 617-582-7646.
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| Contact: |
Claudia Steele
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| Wednesday, February 27, 2013
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11:30 AM - 1:00 PM
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Bioinformatics Seminar Series:RNA conformational switches and the Fast Fourier Transform
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| Description: |
Peter Clote, Boston College
TOC Lab, MIT's Stata Building 32 Room G575
RNA secondary structure forms a scaffold for tertiary structure formation,
hence is a major determinant for both structure and function of an RNA molecule. While protein secondary structure is predicted by machine learning methods, RNA secondary structure can be predicted by dynamic programming methods that use an ab initio energy model will experimentally measured free energy parameters. Such thermodynamics-based methods constitute important tools especially when confronted with novel RNAs of unknown function.
In this talk, we describe two recent results. First, we briefly describe a new algorithm, RNAsc, to optimally predict RNA secondary structure when integrating chemical/enzymatic probing data, such as in-line probing or SHAPE data (selective 2'-hydroxyl acylation analyzed by primer extension). Secondly, we describe a thermodynamics-based algorithm, FFTbor, for conformational switch prediction that employs the FFT to determine partition functions by polynomial interpolation.
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| Contact: |
Patrice Macaluso
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| Thursday, February 28, 2013
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8:00 AM - 5:00 PM
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Health Equity Symposium: Science & Medicine in Africa
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| Description: |
Date: February 28, 2013
Location: Novartis, 250 Massachusetts Avenue, Auditorium, Cambridge, MA 02144
How do we create a new scenario in which every nation in the developing world has the power to improve the health of its population in the face of challenges?
Attend HES 2013 to learn about new, more effective approaches of increasing science and technology capabilities within the developing world.
Keynote Speaker: Sir Nigel Crisp, Member of the UK House of Lords and former Director of the UK National Health Service
Presentations and panel discussions will address the following topics:
• Scientific capability development as a bidirectional effort.
• What industrialized and developing nations can learn from each other
Two visions: the future of basic science and clinical research in Africa
• An in-depth discussion with the audience on open questions and innovative solutions to infrastructure building and capabilities development
• Emerging challenges – dealing with the rise of chronic diseases in Africa and the developing world
• African genome projects - optimizing treatment for genetically diverse populations
• What lessons can be learned from efforts to eradicate disease?
• Exploring the benefits of healthier nations – an economic dividend
For the full program and to register visit www.healthequitysymposium.com
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| Contact: |
Meghan Somers
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12:15 PM - 1:45 PM
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Systems Biology Seminar
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| Description: |
Hongzhe Li, Professor of Biostatistics in Biostatistics and Epidemiology, University of Pennsylvania
All talks to be held in LSE room 103, Boston University (24 Cummington St., Boston, MA) on Thursdays.
A free lunch will begin at 12:15; talks will begin at 12:45 unless otherwise noted.
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| Contact: |
Paige Fults
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Month of February 2013
