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| Wednesday, October 3, 2012
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5:30 PM - 7:00 PM
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MSI Graduate Consortium Reception and Information Session
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| Description: |
Location: Harvard University Center for the Environment (HUCE)- climate change exhibit area/seminar room, 24 Oxford St (Cambridge), 3rd Floor, Room 310
Host: Roberto Kolter
Description: MSI welcomes Harvard graduate students with an interest in any aspect of the microbial sciences to join this vibrant interdisciplinary community. The evening will be an opportunity to socialize with current and prospective members of the consortium and to learn more about the program.
RSVP: to Nora Millan Rivas at nemrivas@fas.harvard.edu
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| Contact: |
Nora Millan Rivas
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6:00 PM - 7:30 PM
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| Thursday, October 4, 2012
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7:00 AM - 5:30 PM
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The 1st Official Conference of ICBS2012
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| Description: |
Keynote lectures
• Stuart Schreiber, HHMI and Broad Institute of Harvard and MIT, US
• Lewis Cantley, Harvard Medical School, US
• Paul Workman, The Institute of Cancer Research, UK
For more information visit www.chemical-biology.org/ICBS2012
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| Contact: |
Lauren Bautista
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9:00 AM - 5:00 PM
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Noon - 1:00 PM
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From Transcription to Morphogenesis: Foxc1, Msx2 and the Patterned Growth of the Mammalian Skull
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| Description: |
Speaker: Robert Maxson, PhD, Professor of Biochemistry & Molecular Biology, Keck School of Medicine USC
Location: The Forsyth Institute, Seminar Rooms A & B, 245 First Street, 17th Floor, Cambridge
Summary: My talk will have two parts. In the first, I will focus on the morphogenetic mechanisms by which the bones of the skull vault grow. I will discuss an interaction between the transcription factors, Foxc1 and Msx2, that has a crucial part in the initial specification of osteoprogenitor cells that give rise to the frontal and parietal bones. We have found that the forkhead transcription factor, Foxc1 regulates the influence of Bmps on the expression of Msx2 and the specification of osteogenic precursor cells in the developing skull vault. Foxc1 acts directly on an Msx2 upstream enhancer to restrict Msx2 expression to an osteogenic zone in the developing frontal bone: In Foxc1 mutants, Msx2 expression, and the osteogenic domain, expand resulting in the premature differentiation of osteogenic precursor cells and the consequent failure of skull vault growth. In the second part of the talk, I will discuss the pathophysiology of craniosynostosis, the fusion of calvarial bones at the sutures. I will describe a regulatory network in which Twist1 and its basic helix loop helix partner, Tcf12, are at the top of a hierarchy, controlling two independent pathways, ephrin-Eph and Jagged1/Notch. Ephrin-Eph functions in the guidance of osteogenic cells to their destinations in the developing frontal and parietal bones. A failure of this process results in mis-migration of osteogenic precursor cells into the coronal suture. Jagged1/Notch functions in the initial specification of sutural cells and in the boundary between the osteogenic and non-osteogenic compartments in the coronal suture. Together these two mechanisms underlie craniosynostosis in Twist1 mutant mice and, we propose, in humans with Twist1 mutations.
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| Contact: |
Pam Quattrocchi
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12:15 PM
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| Friday, October 5, 2012
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(All Day)
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| Wednesday, October 10, 2012
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2:00 PM - 3:20 PM
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| Thursday, October 11, 2012
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12:15 PM - 1:45 PM
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5:30 PM - 6:45 PM
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Writing a History of Cancer: An Epilogue
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| Description: |
37th Annual Joseph Garland Lecture
Speaker: Siddhartha Mukherjee, MD, PhD, Assistant Professor of Medicine at Columbia University and an oncologist at the Columbia University Medical Center.
After studying immunology at Oxford on a Rhodes Scholarship, he received his medical degree from Harvard Medical School. He did an oncology fellowship at the Dana Farber Cancer Institute and was an attending physician at Massachusetts General Hospital. His scientific work addresses the links between normal stem cells and cancer cells.
Dr. Mukherjee is the author of The Emperor of All Maladies: A Biography of Cancer, which won the 2011 Pulitzer Prize for General Nonfiction
Location: Armenise Amphitheatre, Armenise Building, HMS, 200 Longwood Ave., Boston
This lecture is sponsored by the Boston Medical Library in the Francis A. Countway Library of Medicine
For more information please contact Roz Vogel at 617-432-4807 or rvogel@hms.harvard.edu or visit www.countway.harvard.edu
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| Contact: |
Roz Vogel
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5:30 PM - 7:00 PM
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| Monday, October 15, 2012
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1:00 PM - 5:00 PM
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Program in Genetics and Genomics Annual Symposium
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| Description: |
Program in Genetics and Genomics, part of the Biological and Biomedical Sciences graduate program, presents its annual symposium featuring the research of past and current students!
Joseph B. Martin Conference Center, Rotunda Room, third floor, Harvard Medical School
Speakers:
Kit Pogliano, University of CA, San Diego
“The chemical cell biology of interspecies interactions”
Charlotte Wang, Kuroda Laboratory, HMS
“ChIP-mass spectrometry captures protein interactions associated with dosage compensation in Drosophila”
James Sun, Reich Laboratory, HMS
“A direct characterization of human mutation based on microsatellites”
Barak Cohen, Washington University Medical School
“Genomic approaches to understanding combinatorial cis-regulation”
Heidi Rehm, Harvard Medical School
“Delivering genomic medicine: challenges and opportunities”
A poster session and reception follows the talks, 2nd floor lounge
Sponsored by the Division of Medical Sciences W. Eugene Knox III Memorial Lectureship Fund
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| Contact: |
Leah Brault
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4:00 PM
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Functions of the Mst1/Mst2 Protein Kinases in Epithelial and Lymphoid Cells
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| Description: |
MGH/Harvard Cutaneous Biology Research Center Seminar Series
Speaker: Joseph Avruch, M.D., Chief, Diabetes Unit – Massachusetts General Hospital/ Professor of Medicine in the Department of Molecular Biology – Harvard Medical School
Location: MGH East Building 149, Charlestown Navy Yard
Isselbacher Auditorium, 7th Floor
Contact Person: Wendy D. Mohan/ wmohan@partners.org
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| Contact: |
Wendy Mohan
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| Tuesday, October 16, 2012
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Noon - 1:00 PM
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New Paradigms On The Extensive Transport Function Of Maturation Stage Ameloblasts
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| Description: |
Speaker: Michael L. Paine, B.Sc., B.D.S., Ph.D.
Professor, USC Associates Professor of Dentistry, Director of the Graduate Program in Craniofacial Biology, Co-Director of the Masters of Science in Clinical and Biomedical Investigations Division of Biomedical Sciences Center for Craniofacial Molecular Biology, Herman Ostrow School of Dentistry, University of Southern California
Location: The Forsyth Institute, Seminar Rooms A & B, 245 First St., 17th Floor, Cambridge
Abstract: Fully matured dental enamel is an architecturally and mechanically complex hydroxyapatite-based bioceramic devoid of the majority of organic material that was essential in its making. Enamel formation is a staged process largely involving secretory and maturation stages with major changes in gene expression and function between both stages. Cellular activities that define the maturation stage of amelogenesis include ion (e.g. calcium and phosphate) transport and storage, control of intracellular and extracellular pH (e.g. bicarbonate and hydrogen ion movements), and endocytotsis. Recent studies have identified a growing array of gene products that are primarily responsible for many of these cellular events. This review describes the main cellular activities and the newly identified genes associated with maturation stage of amelogenesis. In addition, we briefly discuss the associations between dental diseases related to gene mutations affecting non-dental tissues and organs such cystic fibrosis and others.
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| Contact: |
Pam Quattrocchi
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4:00 PM - 5:00 PM
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Cardiomyocyte Refreshment in Mammalian Heart
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| Description: |
Speaker: Richard T. Lee, M.D.
Professor of Medicine,
Brigham and Women's Hospital
Cardiovascular Seminar Series, Department of Cardiology
Enders Auditorium, Boston Children’s Hospital
This conference is supported by the Faye and Karen Sinclair Research Fund for Congenital Heart Disease
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| Contact: |
michelle merry
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4:00 PM - 5:00 PM
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| Thursday, October 18, 2012
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Noon - 1:00 PM
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To be ORN Notch to be: Epigenetic Control in Olfactory Neurogenesis
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| Description: |
Tufts University Sackler School of Graduate Biomedical Sciences Program in Cell, Molecular and Developmental Biology
Guest Speaker: Adrian W. Moore, PhD, Unit Leader, Disease Mechanism Research Core, RIKEN Brain Science Instititue, Wako, Japan
Location: Stearns Auditorium, Tufts Medical Center, Farnsworth Building, 1st Floor, 800 Washington Street,Boston
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| Contact: |
Sharon Belding
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| Friday, October 19, 2012
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8:30 AM - 9:30 AM
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2:00 PM - 5:30 PM
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Science and Sushi with RIKEN
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| Description: |
This event includes a series of talks by prominent RIKEN neuroscientists followed by a reception with sushi and sake. The group from the RIKEN Brain Science Institute invites Boston-area neuroscientists to explore career opportunities at RIKEN at the undergraduate, postdoctoral, and especially the faculty level.
For more information, visit http://cbs.fas.harvard.edu/resources/activities/%5Bfield_speaker-title%5D-science-and-sushi-riken.
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| Contact: |
Takao Hensch
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| Tuesday, October 23, 2012
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4:00 PM - 5:00 PM
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| Wednesday, October 24, 2012
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Noon - 1:00 PM
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| Thursday, October 25, 2012
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12:15 PM
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Systems Biology Seminar: TBA
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| Description: |
Jason Bohland, Assistant Professor Health Sciences Department Boston University
All talks to be held in LSE room 103, Boston University, 24 Cummington St., Boston, MA.
A free lunch will begin at 12:15; talks will begin at 12:45 unless otherwise noted.
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| Contact: |
Paige Fults
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| Friday, October 26, 2012
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8:30 AM - 9:30 AM
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8:30 AM - 9:30 AM
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| Monday, October 29, 2012
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4:00 PM - 7:00 PM
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Regulatory Science: Perspectives
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| Description: |
In a recent publication from the Institute of Medicine (IOM) entitled, “Strengthening a Workforce for Innovative Regulatory Science in Therapeutics Development”, the Food and Drug Administration (FDA) defines regulatory science as the “science of developing new tools, standards, and approaches to assess the safety, efficacy, quality, and performance of FDA-regulated products.” This symposium will include presentations by four of the leaders in the field of regulatory science:
Location:Merck Auditorium and Atrium (1st floor), 33 Avenue Louis Pasteur, Boston
Janet Woodcock, M.D. (FDA, Center for Drug Evaluation and Research)
Michael Rosenblatt, M.D. (Merck)
Elliott Antman, M.D. (Brigham and Women’s Hospital)
William Fisher, III, J.D., Ph.D. (Harvard Law School)
Following presentations, the audience will be invited to explore these topics further during an hour-long panel, moderated by Joshua Boger, Ph.D. The presentations and panel discussion will be followed by a reception to foster continued discussion. Members of the academic and pharmaceutical industries are welcome to attend.
For more information visit: http://catalyst.harvard.edu/news/news.html?p=4866&title=Register+now+for+Regulatory+Science%3A+Perspectives+–+Part+of+the+Kantoff-Sang+Lecture+Series
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| Contact: |
Eva Konomi
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| Tuesday, October 30, 2012
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12:30 PM - 1:30 PM
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4:00 PM - 5:00 PM
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26th Apffel Memorial Lecture
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| Description: |
Title: Cancel Cell Signaling and Metabolism: Integrated Networks with Emerging Implications for Cancer Therapy
Speaker: Robert T. Abraham, Ph.D., Senior Vice President and Chief Scientific Officer Oncology Research Unit, Pfizer
Location: Beth Israel Deaconess Medical Center Cancer Center Conference Room, Center for Life Science CLS 421
Light reception will follow the lecture in the CLS Lobby
For more information, contact Dr. Antoine Karnoub at akarnoub@bidmc.harvard.edu
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| Contact: |
Cristina Bonilla
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| Wednesday, October 31, 2012
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Noon - 1:00 PM
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2:00 PM - 3:20 PM
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Circadian Clock in Development and Aging: No Time To Lose
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| Description: |
Irina V. Zhdanova, M.D., Ph.D., Professor of Anatomy and Neurobiology, and Principal Investigator in the Laboratory of Sleep and Circadian Physiology at Boston University School of Medicine
Building R-103, Boston University
Note: Free and open to the public. Refreshments will be served on the sixth floor of the R Building at 1:45 P.M.
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| Contact: |
Christina Cherel
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Month of October 2012
