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| Sunday, April 1, 2012
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8:30 AM - 9:30 AM
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| Monday, April 2, 2012
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Noon - 1:00 PM
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Tufts HNRCA Seminar Series ~ Dr. Ed Dennis
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| Description: |
This lecture given by Dr. Ed Dennis of the University of California is titled: Understanding Omega-3 Fatty Acid Function through Lipidomics Analysis of the Macrophage and Plasma Lipidomes.
Seminars will be held at 12 noon in the Auditorium of the HNRCA, Tufts University and will be followed by a student and post-doc luncheon on the 9th floor, 711 Washington St. Boston, MA 02111.
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| Contact: |
John Heine
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3:30 PM - 4:30 PM
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Targeting Wnt Activation in Human Malignancies
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| Description: |
MGH/Harvard Cutaneous Biology Research Center Seminar Series
Speaker - Stuart A. Aaronson, M.D., Department of Oncological Sciences - The Mount Sinai Medical Center
Location: MGH East, Buidling 149, Charlestown Navy Yard
Isselbacher Auditorium, 7th Floor.
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| Contact: |
Kevin J. Travers, B.S.
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| Wednesday, April 4, 2012
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6:00 PM - 7:30 PM
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| Monday, April 9, 2012
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Noon - 1:15 PM
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| Tuesday, April 10, 2012
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12:30 PM - 1:30 PM
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| Tuesday, April 17, 2012
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12:30 PM - 1:30 PM
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| Wednesday, April 18, 2012
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(All Day)
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MDx Next: Molecular Diagnostics Conference
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| Description: |
Practical conference sessions will tackle key questions and hot topics in molecular diagnostic and genetic testing, including:
As molecular markets get increasingly crowded, what are the best testing opportunities, how should they be priced, and do they make financial sense for your laboratory?
How can laboratories best build and optimize their molecular test menus?
With the wave of molecular diagnostics-based partnerships involving diagnostics companies and major pharmaceutical players, where do hospital labs fit in?
How are pharmacogenomics and personalized medicine affecting the interaction of clinical labs and physician practices?
What are the leading risks and challenges you should be aware of in the next two to three years in this market?
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| Contact: |
Stephanie Murg
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| Thursday, April 19, 2012
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(All Day)
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MDx Next: Molecular Diagnostics Conference
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| Description: |
Practical conference sessions will tackle key questions and hot topics in molecular diagnostic and genetic testing, including:
As molecular markets get increasingly crowded, what are the best testing opportunities, how should they be priced, and do they make financial sense for your laboratory?
How can laboratories best build and optimize their molecular test menus?
With the wave of molecular diagnostics-based partnerships involving diagnostics companies and major pharmaceutical players, where do hospital labs fit in?
How are pharmacogenomics and personalized medicine affecting the interaction of clinical labs and physician practices?
What are the leading risks and challenges you should be aware of in the next two to three years in this market?
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| Contact: |
Stephanie Murg
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Noon - 1:00 PM
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What’s in a name? - Genetic and phenotypic heterogeneity in oral pathogens and commensals
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| Description: |
Speaker: Robert A. Burne, PhD, Department of Oral Biology, University of Florida College of Dentistry
Location: The Forsyth Institute, Seminar Room A, 245 First St., 17th Floor, Cambridge
Summary: The development of oral infectious diseases is accompanied by changes in the microbial composition and biochemical activities of oral biofilms. In the case of dental caries, it is known that the initiation and progression of disease is associated with an increase in theproportions of acid-tolerant species, many of which can grow and produce acids at pH values well below those that damage tooth mineral. High throughput technologies have been used effectively to quantify microbial diversity in healthy and carious sites, but clear associations of particular organisms with health and disease are not always apparent or consistent. Studies will be presented that address three major challenges in correlating oral microbiome composition with dental health. The first will detail evolutionary and functional genomic approaches to dissect the basis for phenotypic heterogeneity within the species Streptococcus mutans. The second explores the microbiological and molecular basis for the diminished capacity of oralbiofilms of caries-active subjects to moderate acidification through metabolism of salivary substrates. The third will describe the use of a novel microfluidics-based system to study, at the single cell level, the effects of microenvironments on intercellular communication systems of S. mutans. Collectively, these studies augment ongoing metagenomic approaches by disclosing how genetic heterogeneity and phenotypic plasticity impact the pathogenic potential of oral biofilms
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| Contact: |
Pam Quattrocchi
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3:00 PM - 5:30 PM
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Understanding cancer and other complex traits using physical and genetic networks
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| Description: |
Trey Ideker, PhD
Department of Medicine, University of California, San Diego, USA, 92093-0688
Physical and genetic mapping data have become as important to Network Biology as they were to the Human Genome Project. Physical interaction maps are being constructed through systematic measurements of protein-protein, protein-DNA, and protein-small molecule interactions. Genetic interaction maps are being generated by large-scale screening of synthetic-lethals and epistasis, by multipoint gene association studies, and by mapping the effects of natural and prescribed genetic variations on gene expression. We are working on ways of integrating physical and genetic interaction maps to assemble models of molecular regulatory and signaling networks. We show how these network models can be used to address a variety of biomedical endpoints, including network-based patient stratification, drug target discovery, and genome-wide association studies. These efforts face several challenges, including: increasing the coverage of each type of network; establishing methods to assemble individual interaction measurements into contiguous pathway models; and annotating these pathways with detailed functional information.
Broad Institute
7 Cambridge Center Auditorium (NE30-1154)
3:00 PM - Tea and Reception (Main Lobby)
4:00 PM - Lecture (Auditorium)
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| Contact: |
Linda Hill-White
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| Monday, April 23, 2012
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Noon - 1:00 PM
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Dental Calculus: A Novel Biomolecular Reservoir of Ancient Dietary and Health Indicators
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| Description: |
Speaker: Dr. Christina Warinner, Acting Head of the Molecular Research Group, Centre for Evolutionary Medicine, Institute of Anatomy, University of Zürich
Location: The Forsyth Institute, Seminar Room A, 245 First Street, 17th Floor, Cambridge
Summary: Archaeologists have long been interested in the dietary and health histories of ancient peoples. However, reconstructing these histories using conventional tools can be difficult, indirect, and imprecise. Recent microscopy investigations of dental calculus have shown that this mineralized biofilm is a long-term reservoir of food remnants and oral bacteria. In this paper we present novel data demonstrating that dental calculus is also a robust reservoir of ancient biomolecules, including genomic DNA and proteins. Given the near ubiquity of dental calculus in the archaeological record, the discovery of well-preserved biomolecules within dental calculus promises to greatly expand our understanding of human diet and health in antiquity.
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| Contact: |
Pam Quattrocchi
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| Tuesday, April 24, 2012
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12:30 PM - 1:30 PM
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Intracellular Biology of Salmonella
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| Description: |
David Holden, Imperial College London
Hosted by Michael Starnbach
Warren Alpert Building Room 563, Harvard Medical School
Coffee and snacks served at 12:15 pm outside the room
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| Contact: |
Jessica Conner
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4:00 PM - 5:00 PM
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6:00 PM - 8:30 PM
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MASS-AWIS Careers in Science Event
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| Description: |
Careers in Science
Location: 43 Vassar St, Cambridge, MA 02139 (MIT building 46), 3rd Floor Atrium
MASS AWIS, in conjunction with the Cambridge Science Festival, is hosting a Careers in Science Event for undergrad, grad, postdoc and early career level men and women within the scientific community. This event will be done in a speed networking fashion: 10-15 experienced individuals representing diverse scientific careers will give insight into their chosen profession. Attendees will go to tables with careers they would like to learn more about. Career areas including: Consulting, Patent Law, Research & Development, Technology Transfer, Consulting, Publishing/Medical Writing, Academia, Business Development, Competitive Intelligence, Technical Support Specialist, Teaching, Medical Science Liaison, Human Resources.
Agenda:
6:00-6:30 pm: Registration, Networking and Snacks
6:30-7:00 pm: Introduction of Evening
7:00-8:15 pm: Speed Networking (five 15 min sessions)
8:15-8:30 pm: Networking and Desserts
FOR MORE INFORMATION, VISIT:
http://www.cambridgesciencefestival.org
www.mass-awis.org
TO REGISTER, GO TO:
http://www.acteva.com/go/mass-awis
Admission $35 (AWIS members receive $15 discount)
Join AWIS to save money on events and to support our work!
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| Contact: |
Lynnelle Pittet
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| Thursday, April 26, 2012
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4:00 PM - 5:00 PM
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Astroglial Developmental Maturation and Neurodevelopmental Disorder Fragile X Syndrome (FXS)
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| Description: |
Tufts University Program in Cell, Molecular and Developmental Biology Seminar Series
Guest Speaker: Yongjie Yang, PhD, Department of Neuroscience, Sackler School of Graduate Biomedical Sciences, Tufts University
Location: Tuft Medical Center, Stearns Auditorium, Farnsworth Building, 1st Floor, 800 Washington Street, Boston, MA 02111
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| Contact: |
Sharon Belding
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| Monday, April 30, 2012
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10:00 AM - 11:00 AM
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Novartis Seminar - Autism genetics in mouse and man
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| Description: |
Speaker: Dr. Daniel H. Geschwind, MD, PhD, Professor, Departments of Neurology, Psychiatry and Human Genetics,
Gordon and Virginia MacDonald Distinguished Chair
Director of the Neurogenetics Program and Center for Autism Research and Treatment (CART) Co-Director, UCLA Center for Neurobehavioral Genetics
Location: Novartis, 250 Massachusetts Avenue, Auditorium
Enter on foot between 220 and 250 Massachusetts Avenue. Auditorium is in the second building on your left.
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| Contact: |
Meghan Somers
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Month of April 2012
