| Sunday, April 1, 2012
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8:30 AM - 9:30 AM
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| Monday, April 2, 2012
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Noon - 1:00 PM
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Tufts HNRCA Seminar Series ~ Dr. Ed Dennis
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| Description: |
This lecture given by Dr. Ed Dennis of the University of California is titled: Understanding Omega-3 Fatty Acid Function through Lipidomics Analysis of the Macrophage and Plasma Lipidomes.
Seminars will be held at 12 noon in the Auditorium of the HNRCA, Tufts University and will be followed by a student and post-doc luncheon on the 9th floor, 711 Washington St. Boston, MA 02111.
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| Contact: |
John Heine
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3:30 PM - 4:30 PM
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Targeting Wnt Activation in Human Malignancies
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| Description: |
MGH/Harvard Cutaneous Biology Research Center Seminar Series
Speaker - Stuart A. Aaronson, M.D., Department of Oncological Sciences - The Mount Sinai Medical Center
Location: MGH East, Buidling 149, Charlestown Navy Yard
Isselbacher Auditorium, 7th Floor.
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| Contact: |
Kevin J. Travers, B.S.
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| Wednesday, April 4, 2012
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6:00 PM - 7:30 PM
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| Monday, April 9, 2012
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Noon - 1:15 PM
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| Tuesday, April 10, 2012
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12:30 PM - 1:30 PM
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| Tuesday, April 17, 2012
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12:30 PM - 1:30 PM
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| Wednesday, April 18, 2012
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(All Day)
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MDx Next: Molecular Diagnostics Conference
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| Description: |
Practical conference sessions will tackle key questions and hot topics in molecular diagnostic and genetic testing, including:
As molecular markets get increasingly crowded, what are the best testing opportunities, how should they be priced, and do they make financial sense for your laboratory?
How can laboratories best build and optimize their molecular test menus?
With the wave of molecular diagnostics-based partnerships involving diagnostics companies and major pharmaceutical players, where do hospital labs fit in?
How are pharmacogenomics and personalized medicine affecting the interaction of clinical labs and physician practices?
What are the leading risks and challenges you should be aware of in the next two to three years in this market?
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| Contact: |
Stephanie Murg
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| Thursday, April 19, 2012
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(All Day)
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MDx Next: Molecular Diagnostics Conference
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| Description: |
Practical conference sessions will tackle key questions and hot topics in molecular diagnostic and genetic testing, including:
As molecular markets get increasingly crowded, what are the best testing opportunities, how should they be priced, and do they make financial sense for your laboratory?
How can laboratories best build and optimize their molecular test menus?
With the wave of molecular diagnostics-based partnerships involving diagnostics companies and major pharmaceutical players, where do hospital labs fit in?
How are pharmacogenomics and personalized medicine affecting the interaction of clinical labs and physician practices?
What are the leading risks and challenges you should be aware of in the next two to three years in this market?
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| Contact: |
Stephanie Murg
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Noon - 1:00 PM
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What’s in a name? - Genetic and phenotypic heterogeneity in oral pathogens and commensals
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| Description: |
Speaker: Robert A. Burne, PhD, Department of Oral Biology, University of Florida College of Dentistry
Location: The Forsyth Institute, Seminar Room A, 245 First St., 17th Floor, Cambridge
Summary: The development of oral infectious diseases is accompanied by changes in the microbial composition and biochemical activities of oral biofilms. In the case of dental caries, it is known that the initiation and progression of disease is associated with an increase in theproportions of acid-tolerant species, many of which can grow and produce acids at pH values well below those that damage tooth mineral. High throughput technologies have been used effectively to quantify microbial diversity in healthy and carious sites, but clear associations of particular organisms with health and disease are not always apparent or consistent. Studies will be presented that address three major challenges in correlating oral microbiome composition with dental health. The first will detail evolutionary and functional genomic approaches to dissect the basis for phenotypic heterogeneity within the species Streptococcus mutans. The second explores the microbiological and molecular basis for the diminished capacity of oralbiofilms of caries-active subjects to moderate acidification through metabolism of salivary substrates. The third will describe the use of a novel microfluidics-based system to study, at the single cell level, the effects of microenvironments on intercellular communication systems of S. mutans. Collectively, these studies augment ongoing metagenomic approaches by disclosing how genetic heterogeneity and phenotypic plasticity impact the pathogenic potential of oral biofilms
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| Contact: |
Pam Quattrocchi
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3:00 PM - 5:30 PM
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Understanding cancer and other complex traits using physical and genetic networks
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| Description: |
Trey Ideker, PhD
Department of Medicine, University of California, San Diego, USA, 92093-0688
Physical and genetic mapping data have become as important to Network Biology as they were to the Human Genome Project. Physical interaction maps are being constructed through systematic measurements of protein-protein, protein-DNA, and protein-small molecule interactions. Genetic interaction maps are being generated by large-scale screening of synthetic-lethals and epistasis, by multipoint gene association studies, and by mapping the effects of natural and prescribed genetic variations on gene expression. We are working on ways of integrating physical and genetic interaction maps to assemble models of molecular regulatory and signaling networks. We show how these network models can be used to address a variety of biomedical endpoints, including network-based patient stratification, drug target discovery, and genome-wide association studies. These efforts face several challenges, including: increasing the coverage of each type of network; establishing methods to assemble individual interaction measurements into contiguous pathway models; and annotating these pathways with detailed functional information.
Broad Institute
7 Cambridge Center Auditorium (NE30-1154)
3:00 PM - Tea and Reception (Main Lobby)
4:00 PM - Lecture (Auditorium)
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| Contact: |
Linda Hill-White
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| Monday, April 23, 2012
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Noon - 1:00 PM
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Dental Calculus: A Novel Biomolecular Reservoir of Ancient Dietary and Health Indicators
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| Description: |
Speaker: Dr. Christina Warinner, Acting Head of the Molecular Research Group, Centre for Evolutionary Medicine, Institute of Anatomy, University of Zürich
Location: The Forsyth Institute, Seminar Room A, 245 First Street, 17th Floor, Cambridge
Summary: Archaeologists have long been interested in the dietary and health histories of ancient peoples. However, reconstructing these histories using conventional tools can be difficult, indirect, and imprecise. Recent microscopy investigations of dental calculus have shown that this mineralized biofilm is a long-term reservoir of food remnants and oral bacteria. In this paper we present novel data demonstrating that dental calculus is also a robust reservoir of ancient biomolecules, including genomic DNA and proteins. Given the near ubiquity of dental calculus in the archaeological record, the discovery of well-preserved biomolecules within dental calculus promises to greatly expand our understanding of human diet and health in antiquity.
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| Contact: |
Pam Quattrocchi
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| Tuesday, April 24, 2012
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12:30 PM - 1:30 PM
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Intracellular Biology of Salmonella
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| Description: |
David Holden, Imperial College London
Hosted by Michael Starnbach
Warren Alpert Building Room 563, Harvard Medical School
Coffee and snacks served at 12:15 pm outside the room
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| Contact: |
Jessica Conner
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4:00 PM - 5:00 PM
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6:00 PM - 8:30 PM
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MASS-AWIS Careers in Science Event
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| Description: |
Careers in Science
Location: 43 Vassar St, Cambridge, MA 02139 (MIT building 46), 3rd Floor Atrium
MASS AWIS, in conjunction with the Cambridge Science Festival, is hosting a Careers in Science Event for undergrad, grad, postdoc and early career level men and women within the scientific community. This event will be done in a speed networking fashion: 10-15 experienced individuals representing diverse scientific careers will give insight into their chosen profession. Attendees will go to tables with careers they would like to learn more about. Career areas including: Consulting, Patent Law, Research & Development, Technology Transfer, Consulting, Publishing/Medical Writing, Academia, Business Development, Competitive Intelligence, Technical Support Specialist, Teaching, Medical Science Liaison, Human Resources.
Agenda:
6:00-6:30 pm: Registration, Networking and Snacks
6:30-7:00 pm: Introduction of Evening
7:00-8:15 pm: Speed Networking (five 15 min sessions)
8:15-8:30 pm: Networking and Desserts
FOR MORE INFORMATION, VISIT:
http://www.cambridgesciencefestival.org
www.mass-awis.org
TO REGISTER, GO TO:
http://www.acteva.com/go/mass-awis
Admission $35 (AWIS members receive $15 discount)
Join AWIS to save money on events and to support our work!
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| Contact: |
Lynnelle Pittet
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| Thursday, April 26, 2012
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4:00 PM - 5:00 PM
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Astroglial Developmental Maturation and Neurodevelopmental Disorder Fragile X Syndrome (FXS)
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| Description: |
Tufts University Program in Cell, Molecular and Developmental Biology Seminar Series
Guest Speaker: Yongjie Yang, PhD, Department of Neuroscience, Sackler School of Graduate Biomedical Sciences, Tufts University
Location: Tuft Medical Center, Stearns Auditorium, Farnsworth Building, 1st Floor, 800 Washington Street, Boston, MA 02111
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| Contact: |
Sharon Belding
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| Monday, April 30, 2012
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10:00 AM - 11:00 AM
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Novartis Seminar - Autism genetics in mouse and man
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| Description: |
Speaker: Dr. Daniel H. Geschwind, MD, PhD, Professor, Departments of Neurology, Psychiatry and Human Genetics,
Gordon and Virginia MacDonald Distinguished Chair
Director of the Neurogenetics Program and Center for Autism Research and Treatment (CART) Co-Director, UCLA Center for Neurobehavioral Genetics
Location: Novartis, 250 Massachusetts Avenue, Auditorium
Enter on foot between 220 and 250 Massachusetts Avenue. Auditorium is in the second building on your left.
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| Contact: |
Meghan Somers
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| Tuesday, May 1, 2012
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Noon - 1:00 PM
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Tufts HNRCA Seminar Series ~ Susan Roberts and Sai Das
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| Description: |
This lecture by Drs. Susan Roberts and Sai Das is titled: Worksite Interventions for Weight Control.
Seminars will be held at 12 noon in the Auditorium of the HNRCA and will be followed by a student and post-doc luncheon on the 9th floor,711 Washington St. Boston, MA 02111.
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| Contact: |
John Heine
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12:30 PM - 1:30 PM
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4:00 PM - 5:00 PM
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Armen H. Tashjian, Jr. Award for Excellence in Endocrine Research
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| Description: |
Armen H. Tashjian, Jr. Award for Excellence in Endocrine Research
Presentation and Lecture
Please join us in celebrating this year’s award recipient:
Chih-Hao Lee, Ph.D., Associate Professor, Department of Genetics and Complex Diseases
presenting a lecture entitled:
“Endocrine control of metabolism by lipid and inflammatory signaling"
Location: Kresge G2, Harvard School of Public Health
reception to follow
To honor his many accomplishments, the friends and family of Dr. Armen H. Tashjian, Jr., Professor of Toxicology, Emeritus, in the Department of Genetics and Complex Diseases, have established an award in his name to assist faculty and fellows to pursue innovative research ideas in basic biomedical sciences.
For additional information, or to request a HSPH visitor’s pass, please contact Holly Southern at 617-432-3763.
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| Contact: |
Holly Southern
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4:00 PM - 5:00 PM
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Nanotechnology for drug delivery and tissue engineering
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| Description: |
Tufts University Program in Cell, Molecular and Developmental Biology Seminar Series
Guest Speaker: Qiaobing Xu, PhD, Department of Biomedical Engineering, Tufts University School of Engineering
Location: Tufts University Jaharis Building, 150 Harrison Avenue, Room 508, Boston, MA 02111
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| Contact: |
Sharon Belding
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4:00 PM - 5:00 PM
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Seminars in Oncology: New Determinants of Malignant Progression
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| Description: |
EMILY FREDERICK DIMAGGIO LECTURE
Guest Speaker: Doug Hanahan, Ph.D., Director, Swiss Institute for Experimental Cancer Research Professor of Molecular Oncology Ecole Polytechnique Federale de Lausanne, Switzerland
Location: Jimmy Fund Auditorium (35 Binney Street), Dana-Farber Cancer Institute
Hosted by: Peter Sicinski, MD, PhD
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| Contact: |
Claudia Steele
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| Wednesday, May 2, 2012
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Noon - 1:00 PM
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| Thursday, May 3, 2012
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11:00 AM - Noon
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Invasion and Trafficking of Porphyromonas gingivalis in Human Cardiovascular Endothelial Cells
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| Description: |
Speaker: Ann Progulske-Fox, Ph.D, University of Florida College of Dentistry
Location: The Forsyth Institute, Seminar Room A, 245 First Street, 17th Floor, Cambridge
Summary: Most strains of P. gingivalis invade human endothelial cells, including human cardiovascular aortic endothelial cells (HCAEC). Shortly after entry of P. gingivalis into the host cell, the bacteria traffic to the autophagic pathway and usurp the pathway for their own benefit and survival. Interestingly, P. gingivalis is able to turn on the autophagic pathway before it enters the cell and does not require attachment of the bacteria to the host cells. We have begun to decipher the mechanisms that P. gingivalis uses to control the host cell’s pathway and have identified bacterial genes that are necessary for this process. Such information will be useful for understanding the interactions of P. gingivalis and host cells in vivo, whether related to cardiovascular or periodontal diseases.
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| Contact: |
Pam Quattrocchi
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1:00 PM - 4:00 PM
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Personal Genetics: Discussions about Technology, Inheritance, Medicine and Society
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| Description: |
Personal genetics and genomics is a rapidly evolving branch of genomics in which individual genomes are analyzed to predict associations with disease or other traits of interest, giving individuals information they can use to make decisions about lifestyle, ancestry or medical care. While the potential benefits of personal genetics are vast, this field also raises questions about educational priorities and approaches, privacy, access to information, and psychological impacts. This course will address the societal ramifications related to personal genetics and genomics in diverse fields such as law, reproductive technology, public policy, and research ethics. Course lecturers will summarize the state of personal genetics in the scientific field and in our society and draw from real-life and historical situations to illustrate the knowledge and misconceptions common to the public. We will look at examples from the fields of athletics and forensics to illuminate larger questions around how greater access to DNA might impact society. The aim of this nanocourse is to augment the capacity of our communities to make informed choices as we enter a new era of personal genetics.
Location: Location: Armenise Bldg (D) Amphitheater, Harvard University
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| Contact: |
Leah Brault
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| Friday, May 4, 2012
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10:00 AM - 11:00 AM
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The Monroe Schlesinger Lecture
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| Description: |
Presented by BIDMC's Department of Pathology
Speaker: Richard O. Hynes, PhD, Daniel K. Ludwig Professor for Cancer Research, Massachusetts Institute of Technology
Title: "Cellular and Acellular Influences on Metastasis"
Location: Folkman Auditorium, Enders Research Building, Children's Hospital, 300 Longwood Avenue, Boston
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| Contact: |
Nicole Magner
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Month of April 2012
