| Monday, February 27, 2012
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8:00 AM - 6:00 PM
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IQPC’s Cancer Immunotherapy Conference
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| Description: |
IQPC’s Cancer Immunotherapy Conference
Date: February 27-29, 2012 (8 am to 6 pm)
Location: Metro Meeting Centers, 101 Federal St, Boston
Dr Grace Wong (CEO of ActoKine Therapeutics) is a speaker for this cancer immunotherapy conference on Feb 27-29, 2012 in Boston, she will have 10 free guest passes for student, postdoc & scientists.
Apply for a free pass at www.nobel-pauling.org.
Confirmed Speakers Include:
Grace Wong, PhD, CEO, ActoKine Therapeutics
John Rothman, PhD, Executive VP: Science and Operations, Advaxis Inc.; Ramana Davuluri, PhD, Molecular and Cellular Oncogenesis Program, Wistar Institute; Elma Hawkins, PhD, Head of Clinical Development, ImmunoCellular Therapeutics;
Jeffrey Schlom, PhD, Chief, Laboratory of Tumor Immunology and Biology, NCI; James Gulley, MD, PhD, Director, Laboratory of Tumor Immunology and Biology, NCI;
Dirk Brockstedt, PhD, SVP, Research & Development, Aduro BioTech;Anthony Madia, PhD, MA, MBA, COO, Northwest Biotherapeutics, Inc.; Eric von Hofe, PhD, President, Antigen Express; Ken Brasel, Scientist II, Dendreon Corporation;
Leisha Emens, MD, PhD, Professor, Oncology, Johns Hopkins University of Medicine; David Avigan, MD, Hematology-Oncology, Beth Israel Deaconess Medical Center; Nicola La Monica, PhD, VP, Idera Pharmaceuticals;
John Vasilakos, PhD, Sr. Research Immunologist & Business Director, 3M Company;Mohamed Hussein, MD, VP, Medical Affairs, Celgene; Zihai Li, MD, PhD, Professor, Microbiology & Immunology, University of South Carolina
For more information visit http://www.cancerimmunotherapyevent.com/Event.aspx?id=623580
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| Contact: |
Alex Pauling
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| Tuesday, February 28, 2012
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12:30 PM - 1:30 PM
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When Autophagy Meets Microbes
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| Description: |
Jae Jung, University of Southern California
Hosted by Ronald Desrosiers
Warren Alpert Building Room 563, Harvard Medical School
Coffee and snacks served at 12:15 pm outside the room
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| Contact: |
Jessica Conner
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4:00 PM - 5:00 PM
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| Wednesday, February 29, 2012
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11:30 AM - 1:00 PM
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Bioinformatics Seminar Series: Shape Shifting: protein statistical physics as a linear programming problem
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| Description: |
Jeremy England, MIT
TOC Lab STATA Center 32-G575
Since a protein's shape typically provides the basis for its function, the conformational rearrangements of proteins in response to ligand binding, mutation, and covalent modification very often underlie biologically important molecular events, whether in the normal course of transducing a signal or through deleterious misfolding. A new analytical model of how structure depends on sequence enables us to use linear programming to examine many of these phenomena from the standpoint of statistical mechanics, so that we may begin to predict and explain specific changes in protein structure ranging from allosteric motion to the onset of aggregation disease.
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| Contact: |
Patrice Macaluso
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| Thursday, March 1, 2012
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5:00 PM - 7:00 PM
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Beneath the Surface: The Development and Cultural Impact of Radiology
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| Description: |
Join us for an exploration of the history of radiology, including the development of the X-ray, the pioneering “radiology martyrs,” and radiology’s pervasive influence on visual culture.
More information, including our speakers, can be found here: https://cms.www.countway.harvard.edu/wp/?p=5078
All are welcome! RSVP to the Center for the History of Medicine, Countway Library: contactchom@hms.harvard.edu or 617-432-2170.
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| Contact: |
Heather Cristiano
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| Friday, March 2, 2012
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8:30 AM - 9:30 AM
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Microbial symbioses: Marine bacteria and microalgae
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| Description: |
MSI Weekly Chalktalk. Please join us for coffee/tea and pastries at 8:30, followed by the chalktalk at 8:45AM.
Speaker: Mohammad Seyedsayamdost (HMS-BCMP)
Location: Harvard Center for the Environment (HUCE), 24 Oxford St, 3rd Floor, Room 310
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| Contact: |
Andrea Lenco
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| Tuesday, March 6, 2012
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Noon - 1:00 PM
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12:30 PM - 1:30 PM
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| Wednesday, March 7, 2012
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Noon - 1:00 PM
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Homeostasis in cluster of epithelial cell rest of Malassez maintain by putative epithelial stem cells
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| Description: |
Masaki Honda, DDS., Ph.D., Associate Professor, Department of Anatomy, Nihon University School of Dentistry, Japan
Location: The Forsyth Institute, Seminar Rm. A, 245 First St., 17th Fl., Cambridge
Summary: The fragmented epithelial cells of the Hertwig's epithelial root sheath are retained in the periodontal ligament (PDL) where they persist in small clusters known as epithelial cell rest of Malassez (ERM). It is generally agreed that ERM is maintained as a quiescent and exclusively dental epithelial cluster in PDL, however, we speculate that homeostasis underlies the mechanism of maintaining the cluster. We also hypothesize that the fate of ERM clusters, diminishing or remaining, might be regulated via the presence or absence of epithelial stem cells in ERM clusters.
In fact, ERM clusters in the PDL of mouse first molars gradually increased in size with age until postnatal day 270. Immunocytochemistry and cell culturing to examine the cellular activity of ERM cells revealed KI67-positive cells and ERM cells that had migrated from PDL, expanded by culturing. Apoptosis was also detected in ERM clusters by TUNEL staining. Finally, we identified putative epithelial stem cells in the ERM clusters using two strategies: BrdU pulse-chase experiments. These results ssugested that the clusters of ERM are maintaining via frequent cellular turnover in the PDL throughout life.
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| Contact: |
Pam Quattrocchi
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6:00 PM - 7:30 PM
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Linguistic and cognitive profiles in autism and the broad autism phenotype
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| Description: |
Molly Losh, Ph.D., Jane Steiner Hoffman and Michael Hoffman Assistant Professor, Northwestern University
Please RSVP to lmavros@mit.edu
Visit website for talk abstract: web.mit.edu/autism
The Simons Center for the Social Brain Colloquium Series
is a continuation of the Simons Initiative on Autism and the Brain’s Autism and Developmental Disorders Colloquium Series at MIT (web.mit.edu/autism).
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| Contact: |
Lee Mavros Rushton
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| Thursday, March 8, 2012
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Noon - 1:00 PM
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A gene-to-molecule approach to discovering and characterizing small molecules from microbes
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| Description: |
Speaker: Michael Fischbach, PhD, University of California, San Francisco
Location: The Forsyth Institute, Seminar Room A, 245 First St., 17th Fl., Cambridge
Abstract: The discovery of natural products – small molecules from microbes often used as drugs – has been an ad hoc pursuit for almost a century. The rapidly growing database of microbial genome sequences offers new opportunities to leverage genomics and bioinformatics toward discovering natural products and characterizing their roles in mediating interspecies interactions. This lecture will describe three convergent, ongoing lines of research: our use of genomics and bioinformatics to identify biosynthetic genes and predict the structures of their small molecule products, our characterization of a new class of biosynthetic gene clusters that produce a set of heavily modified peptide antibiotics, and our efforts to identify and characterize small molecules produced by human-associated microbes.
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| Contact: |
Pam Quattrocchi
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5:30 PM - 7:00 PM
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Microbial Facebook: probing bacterial social networks
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| Description: |
MSI Monthly Thursday Seminar. Please join us for a wine and cheese reception at 5:30, followed by the seminar at 6:00PM.
Speaker: Marvin Whiteley (University of Texas at Austin)
Location: HUCE (Harvard Center for the Environment) at 24 Oxford St, 3rd Floor, Room 310
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| Contact: |
Andrea Lenco
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| Tuesday, March 13, 2012
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12:30 PM - 1:30 PM
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| Tuesday, March 20, 2012
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12:30 PM - 1:30 PM
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| Wednesday, March 21, 2012
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1:00 PM - 2:00 PM
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Weight Loss Interventions for Adults with Depression
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| Description: |
Department of Health Sciences
Research Seminar Series Presents: Weight Loss Interventions for Adults with Depression
Sherry Pagoto, University of Massachusetts Medical School
Preventive and Behavioral Medicine
Room 300, Sargent College, Boston University, 635 Commonwealth Avenue
HOST: Dr. Linda Bandini
Refreshments will be served
For more information on Dr. Pagoto go to:
UMASS Profile
http://profiles.umassmed.edu/profiles/ProfileDetails.aspx?From=SE&Person=1013
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| Contact: |
Danka Charland
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| Thursday, March 22, 2012
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5:30 AM - 7:00 PM
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Women in Biotech Panel Discussion
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| Description: |
The Harvard Biotech Club & The DMS Biotech Pathway
Presents Women in Biotech Panel Discussion
Fred S. Rosen Lecture Hall 100A, Modell Immunology Center, inside the Armenise building, Harvard Medical School, 200 Longwood Avenue, Boston
Keynote Speaker:
Daphne Zohar, Founder and Managing Partner, Puretech Ventures
Panelists:
Todd and Jill Milne (Founder, Ironwood & CEO, Catabasis)
Theresa Podrebarac (VP of Medical Research, Biogen Idec)
Jessica Flechtner (VP of Research, Genocea)
Moderator:
Mari Anne Snow, AWIS
Come and meet distinguished women leaders in the biotech industry and learn about their path to success, what they have learned, and how they have balanced their personal lives with their careers. Our stellar group of panelists includes a venture capitalist, biotech entrepreneurs, and executive leaders from biotech/pharma companies.
Men are invited and encouraged to attend!
A light dinner will be served.
This event is free for all Harvard students and Harvard/Harvard hospital affiliated postdoctoral fellows. For non-Harvard affiliated attendees, registration is $10 to be paid at the door.
To register – send an email to thebiotechclub.rsvp@gmail.com with ‘Women in Biotech’ in the subject line by March 18th.
Visit our website for more event information: www.thebiotechclub.org
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| Contact: |
Ketki Verkhedkar
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| Friday, March 23, 2012
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8:30 AM - 9:30 AM
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| Tuesday, March 27, 2012
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12:30 PM - 1:30 PM
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4:00 PM - 5:00 PM
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| Thursday, March 29, 2012
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Noon - 1:00 PM
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Porphyromonas gingivalis lipids: Relationship to Chronic Periodontitis
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| Description: |
Speaker: Frank C. Nichols, PhD, University of Connecticut School of Dental Medicine
Location: The Forsyth Institute, Seminar Room A, 245 First Street, 17th Floor, Cambridge
Summary: This presentation will focus on bacterial virulence factors that are recovered in diseased periodontal tissues by comparing and contrasting the recovery of lipopolysaccharide versus complex lipids of Porphyromonas gingivalis in healthy or diseased tissue samples. Next, the classes of phosphorylated sphingolipids produced by Porphyromonas gingivalis that are recovered in diseased tissues will be discussed. The important biological responses of these lipids and their relevance to chronic periodontitis will be summarised. Biological responses will include proinflammatory, cell death and bone destructive effects of these lipids. Finally, the presentation will show the capacity of the lipids derived from P. gingivalis to engage Toll-like receptor 2 in mediating some of these responses.
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| Contact: |
Pam Quattrocchi
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4:00 PM - 5:00 PM
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The Electric Face: A Role for Bioelectricity in Craniofacial Morphogenesis
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| Description: |
Tufts University Program in Cell, Molecular and Developmental Biology Seminar Series
Guest Speaker: Laura Vandenberg, PhD, Postdoctoral Fellow, Center for Regenerative & Developmental Biology, Tufts University
Location: Stearns Auditorium, Tufts Medical Center, Farnsworth Building, 1st floor, 800 Washington Street, Boston
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| Contact: |
Sharon Belding
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7:00 PM - 9:00 PM
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Life Redesigned: The Emergence of Synthetic Biology
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| Description: |
IEEE Computer Society and GBC/ACM
Location: Broad Institute Auditorium (MIT building NE-30)
Life Redesigned: The Emergence of Synthetic Biology
J.J. Collins, Howard Hughes Medical Institute, Dept. of Biomedical Engineering and Center for BioDynamics, Boston University, Wyss Institute for Biologically Inspired Engineering, Harvard University
Synthetic biology is bringing together engineers and biologists to design and construct biological circuits out of proteins, genes and other bits of DNA, and to use these circuits to rewire and reprogram organisms. These re-engineered organisms are going to change our lives in the coming years, leading to cheaper drugs, "green" means to fuel our car and clean our environment, and targeted therapies to attack "superbugs" and diseases such as cancer. In this talk, we highlight recent efforts to create synthetic gene networks and programmable cells, and discuss a variety of synthetic biology applications in biocomputing, biotechnology and biomedicine.
James J. Collins is an Investigator of the Howard Hughes Medical Institute, and a William F. Warren Distinguished Professor, University Professor, Professor of Biomedical Engineering, Professor of Medicine and Co-Director of the Center for BioDynamics at Boston University. He is also a core founding faculty member of the Wyss Institute for Biologically Inspired Engineering at Harvard University. His research group works in synthetic biology and systems biology, with a particular focus on network biology approaches to antibiotic action and bacterial defense mechanisms. Professor Collins' patented technologies have been licensed by over 25 biotech, pharma and medical devices companies, and he has helped to launched a number of companies, including Novophage and Joule Unlimited. He has received numerous awards and honors, including a Rhodes Scholarship, a MacArthur "Genius" Award, an NIH Director's Pioneer Award, the World Technology Award in Biotechnology, as well as numerous teaching awards. In 2011, Professor Collins was elected to the National Academy of Engineering for "contributions to synthetic biology and engineered gene networks".
This joint meeting of the Boston Chapter of the IEEE Computer Society and GBC/ACM will be held in the Broad Institute Auditorium (MIT building NE-30). The Broad Institute is on Main St between Vassar and Ames streets. You can see it on a map at this location. The auditorium is on the ground floor near the entrance.
Up-to-date information about this and other talks is available online at http://ewh.ieee.org/r1/boston/computer/. You can sign up to receive updated status information about this talk and informational emails about future talks at http://mailman.mit.edu/mailman/listinfo/ieee-cs, our self-administered mailing list.
For more information contact Peter Mager (p.mager at computer.org)
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| Contact: |
Peter Mager
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| Friday, March 30, 2012
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8:30 AM - 9:30 AM
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Chemical Microbial Ecology
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| Description: |
Microbial Sciences Initiative (MSI) weekly chalktalk breakfast. Please join us for tea/coffee and pastries at 8:30, followed by the chalktalk at 8:45.
Speaker: Elizabeth Shank (HMS-MI)
Location: HUCE Seminar Room (24 Oxford St, 3rd Floor, Room 310)
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| Contact: |
Andrea Lenco
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Month of March 2012
