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Sun Mon Tue Wed Thu Fri Sat
8:30 AM - 5:00 PM 29th Annual Critical Issues in Tumor Microenvironment, Angiogenesis, Metastasis and Immunology

4:00 PM - 5:00 PM Genes, networks and variations in innate immunity

8:30 AM - 5:00 PM 29th Annual Critical Issues in Tumor Microenvironment, Angiogenesis, Metastasis and Immunology

3:30 PM - 5:30 PM 12 Tricks Confident People Use to Overcome Impostor Syndrome

1
8:30 AM - 5:00 PM 29th Annual Critical Issues in Tumor Microenvironment, Angiogenesis, Metastasis and Immunology

2
8:30 AM - 5:00 PM 29th Annual Critical Issues in Tumor Microenvironment, Angiogenesis, Metastasis and Immunology

2:00 PM - 5:30 PM Warren Alpert Foundation Prize Symposium: Neurotransmission in Health and Disease

5:30 PM - 7:00 PM Commercializing Innovation: A Primer on Venture Capital

3
4
5
6
Noon - 1:00 PM Northeastern University Biology Colloquia Series: "Inverting E3 ligase function to study plant circadian rhythms"

7
4:00 PM - 5:00 PM Seminars In Oncology: "Reprogramming of Metabolic Myc-Dependencies via a Histone Demethylase Inhibitor"

8
9
6:00 PM - 7:00 PM Microbial Sciences Initiative (MSI) Seminar: J. Taylor

4:00 PM - 5:00 PM MOLECULAR MEDICINE SEMINAR SERIES: Shadow enhancers enable a complex transcriptional circuit in Drosophila embryos

4:00 PM - 5:00 PM Distinguished Lecture Seminar Series "Spatial neglect, the brain, and rehabilitation"

8:30 AM - 9:30 AM Microbial Sciences Initiative (MSI) Chalktalk: I. Castañeda

4:00 PM - 5:00 PM Shared VH1-46 gene usage in pemphigus vulgaris: implications for disease development

8:00 AM - 5:00 PM The Hallmarks of Cancer Symposium

8:30 AM - 9:30 AM Microbial Sciences Initiative (MSI) Chalktalk: N. Joshi

9:30 AM - 1:00 PM Next Generation Sequencing Technologies: Principles and Applications Nanocourse

1
Monday, September 29, 2014
8:30 AM - 5:00 PM
29th Annual Critical Issues in Tumor Microenvironment, Angiogenesis, Metastasis and Immunology
Description: Approval of multiple molecularly targeted agents for therapy of cancer and other diseases has heralded a new era. For tumor biology, the major challenges in the field are now how to optimally use these novel drugs as monotherapies or in combination with other therapies to extend the survival advantage obtained so far, and how to prevent tumor recurrence. These may be best achieved by bringing back and forth between bench and bedside the lessons and the new concepts that emerged from the recent clinical and preclinical experience with molecularly targeted agents. The objective of this course is to discuss our current understanding of tumor microenvironment, the formation and function of new vessels in tumors, and their relationship with metastasis and outcome of various treatments. The focus will be placed on their pathophysiological significance and clinical relevance, with particular emphasis on clinical translation and biomarkers. At the end of this course participants will be able to: Evaluate molecularly targeted agents and immunotherapies approved or currently in clinical development for cancer treatment. Assess relevant, state-of-the-art or translational pre-clinical models of anti-cancer therapies. Recognize the steps and determinants of the metastatic process of cancer. Compare correlative studies of biomarkers and their response and resistance to targeted therapies in cancer patients. Analyze state of the art imaging techniques and their applications in pre-clinical and clinical studies will be taught. Accreditation Harvard Medical School is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. Harvard Medical School designates this educational activity for a maximum of 24 AMA PRA Category 1 Credit(s)™. Physicians should only claim credit commensurate with the extent of their participation in the activity.
Contact: Rakesh K. Jain, PhD
4:00 PM - 5:00 PM
Genes, networks and variations in innate immunity
Description: MGH/Harvard Cutaneous Biology Research Center Seminar Series

Nir Hacohen, PhD Associate Professor of Medicine, Massachusetts General Hospital Center for Immunology and Inflammatory Diseases
MGH-East -- Building 149 13 Street, Charlestown Navy Yard, 7th floor, Isselbacher Auditorium
Registration at Lobby Security Desk Required
Contact: Vivian Theodoracopoulos
Tuesday, September 30, 2014
8:30 AM - 5:00 PM
29th Annual Critical Issues in Tumor Microenvironment, Angiogenesis, Metastasis and Immunology
Description: Approval of multiple molecularly targeted agents for therapy of cancer and other diseases has heralded a new era. For tumor biology, the major challenges in the field are now how to optimally use these novel drugs as monotherapies or in combination with other therapies to extend the survival advantage obtained so far, and how to prevent tumor recurrence. These may be best achieved by bringing back and forth between bench and bedside the lessons and the new concepts that emerged from the recent clinical and preclinical experience with molecularly targeted agents. The objective of this course is to discuss our current understanding of tumor microenvironment, the formation and function of new vessels in tumors, and their relationship with metastasis and outcome of various treatments. The focus will be placed on their pathophysiological significance and clinical relevance, with particular emphasis on clinical translation and biomarkers. At the end of this course participants will be able to: Evaluate molecularly targeted agents and immunotherapies approved or currently in clinical development for cancer treatment. Assess relevant, state-of-the-art or translational pre-clinical models of anti-cancer therapies. Recognize the steps and determinants of the metastatic process of cancer. Compare correlative studies of biomarkers and their response and resistance to targeted therapies in cancer patients. Analyze state of the art imaging techniques and their applications in pre-clinical and clinical studies will be taught. Accreditation Harvard Medical School is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. Harvard Medical School designates this educational activity for a maximum of 24 AMA PRA Category 1 Credit(s)™. Physicians should only claim credit commensurate with the extent of their participation in the activity.
Contact: Rakesh K. Jain, PhD
3:30 PM - 5:30 PM
12 Tricks Confident People Use to Overcome Impostor Syndrome
Description: Defeat career complacency and trade self-doubt for success in the STEM industry. Realize your full potential at:

12 Tricks Confident People Use to Overcome Impostor Syndrome

When: Tuesday, September 30, at 3:30 pm

Where: BU School of Medicine, Evans Building, Wilkins Board Room 1st Floor

Dr. Isaiah Hankel, Ph.D. has unlocked the mysteries of the mind and developed 12 key strategies that will enable you to beat Impostor Syndrome and achieve your greatest professional aspirations

This seminar teaches you to:

• Take control of your life, career and success
• Discover the power of internal validation
• Break any cycles of self-sabotage
• Conquer anxiety, poor performance, and low self esteem
• Utilize "the art of pretending" as a tool for personal advancement
• Maximize your personal and professional potential
• Understand how, by allowing yourself to succeed, you allow others to succeed

SPACE IS LIMITED
TO REGISTER AND FOR MORE INFORMATION, VISIT www.massawis.org/ImpostorSyndrome2014
AWlS MEMBERS $15 • NON-MEMBERS $20 • BU students Free

Register before September 16th for a chance to win Dr. Hankel's new book – Black Hole Focus!
Contact: Lynnelle Pittet
Wednesday, October 1, 2014
8:30 AM - 5:00 PM
29th Annual Critical Issues in Tumor Microenvironment, Angiogenesis, Metastasis and Immunology
Description: Approval of multiple molecularly targeted agents for therapy of cancer and other diseases has heralded a new era. For tumor biology, the major challenges in the field are now how to optimally use these novel drugs as monotherapies or in combination with other therapies to extend the survival advantage obtained so far, and how to prevent tumor recurrence. These may be best achieved by bringing back and forth between bench and bedside the lessons and the new concepts that emerged from the recent clinical and preclinical experience with molecularly targeted agents. The objective of this course is to discuss our current understanding of tumor microenvironment, the formation and function of new vessels in tumors, and their relationship with metastasis and outcome of various treatments. The focus will be placed on their pathophysiological significance and clinical relevance, with particular emphasis on clinical translation and biomarkers. At the end of this course participants will be able to: Evaluate molecularly targeted agents and immunotherapies approved or currently in clinical development for cancer treatment. Assess relevant, state-of-the-art or translational pre-clinical models of anti-cancer therapies. Recognize the steps and determinants of the metastatic process of cancer. Compare correlative studies of biomarkers and their response and resistance to targeted therapies in cancer patients. Analyze state of the art imaging techniques and their applications in pre-clinical and clinical studies will be taught. Accreditation Harvard Medical School is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. Harvard Medical School designates this educational activity for a maximum of 24 AMA PRA Category 1 Credit(s)™. Physicians should only claim credit commensurate with the extent of their participation in the activity.
Contact: Rakesh K. Jain, PhD
Thursday, October 2, 2014
8:30 AM - 5:00 PM
29th Annual Critical Issues in Tumor Microenvironment, Angiogenesis, Metastasis and Immunology
Description: Approval of multiple molecularly targeted agents for therapy of cancer and other diseases has heralded a new era. For tumor biology, the major challenges in the field are now how to optimally use these novel drugs as monotherapies or in combination with other therapies to extend the survival advantage obtained so far, and how to prevent tumor recurrence. These may be best achieved by bringing back and forth between bench and bedside the lessons and the new concepts that emerged from the recent clinical and preclinical experience with molecularly targeted agents. The objective of this course is to discuss our current understanding of tumor microenvironment, the formation and function of new vessels in tumors, and their relationship with metastasis and outcome of various treatments. The focus will be placed on their pathophysiological significance and clinical relevance, with particular emphasis on clinical translation and biomarkers. At the end of this course participants will be able to: Evaluate molecularly targeted agents and immunotherapies approved or currently in clinical development for cancer treatment. Assess relevant, state-of-the-art or translational pre-clinical models of anti-cancer therapies. Recognize the steps and determinants of the metastatic process of cancer. Compare correlative studies of biomarkers and their response and resistance to targeted therapies in cancer patients. Analyze state of the art imaging techniques and their applications in pre-clinical and clinical studies will be taught. Accreditation Harvard Medical School is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. Harvard Medical School designates this educational activity for a maximum of 24 AMA PRA Category 1 Credit(s)™. Physicians should only claim credit commensurate with the extent of their participation in the activity.
Contact: Rakesh K. Jain, PhD
2:00 PM - 5:30 PM
Warren Alpert Foundation Prize Symposium: Neurotransmission in Health and Disease
Description: Neurotransmission in Health and Disease

In honor of Oleh Hornykiewicz, MD, Roger A. Nicoll, MD, Solomon H. Snyder, MD for their seminal contribution to our understanding of neuro transmission and Neurodegeneration.

Harvard Medical School, The Joseph B.Martin Conference Center, 77 Avenue Louis Pasteur, Boston

Open to the public: RSVP to HMS_events@hms.harvard.edu

Symposium Program

Opening Remarks:
Jeffrey S. Flier, MD, Dean of Faculty, Harvard Medical School

Co-Moderators:
Rachel Wilson, PhD,Professor, Department of Neurobiology, Harvard Medical School

David Ginty, PhD, Edward R. and Anne G. Lefler Professor of Neurobiology, HMS, Investigator, Howard Hughes Medical Institute

Prize Recipients

Remarks and Reflections:
Oleh Hornykiewicz, MD, Professor Emeritus Medical University of Vienna and University of Toronto

Solomon H. Snyder, MD, Distinguished Service Professor of Neuroscience, Pharmacology and Psychiatry, Johns Hopkins School of Medicine

Roger A. Nicoll, MD, Professor, University of California, San Francisco School of Medicine

Invited Speakers:
John Williams, PhD, Senior Scientist, Vollum Institute Oregon Health & Sciences University
"G-protein Coupled Receptor dependent synaptic transmission"

Anatol Kreitzer, PhD, Associate Investigator, Gladstone Institutes, University of California, San Francisco
"Circuit Mechanisms Underlying Basal Ganglia Function and Dysfunction"

Beth Stevens, PhD, Assistant Professor, FM Kirby Neurobiology Center, Boston Children's Hospital, Harvard Medical School
"Immune Mechanisms of Synapse Loss in Health and Disease"
Contact: Edward Canton
5:30 PM - 7:00 PM
Commercializing Innovation: A Primer on Venture Capital
Description: Harvard Innovation Lab - 125 Western Ave, Boston, Harvard Business School Campus (We will have a direct "Longwood to i-lab" bus for this event.)

99% of startups will not get venture capital. Is your startup in the 1%? Learn how to increase your probability of starting a successful startup with Lou Berneman, Founding Partner, Osage University Partners. He will discuss how VCs approach investments and how funds, like Osage's, work with entrepreneurs and technology transfer offices to support university-originated startups. Reception immediately following.
Contact: Anna-Rose Stember
Monday, October 6, 2014
Noon - 1:00 PM
Northeastern University Biology Colloquia Series: "Inverting E3 ligase function to study plant circadian rhythms"
Description: Joshua Gendron, Ph.D. Department of Molecular, Cellular, and Developmental Biology, Yale University (http://gendronlab.yale.edu)
90 SNELL LIBRARY, Northeastern University Boston
Contact: Janeen Greene
Tuesday, October 7, 2014
4:00 PM - 5:00 PM
Seminars In Oncology: "Reprogramming of Metabolic Myc-Dependencies via a Histone Demethylase Inhibitor"
Description: Guest Speaker: Udo Oppermann, MD, Professor of Molecular Biology, University of Oxford, Oxford, CA
Jimmy Fund Auditorium, Dana-Farber Cancer Institute
Contact: Claudia Steele
Thursday, October 9, 2014
6:00 PM - 7:00 PM
Microbial Sciences Initiative (MSI) Seminar: J. Taylor
Description: MSI Seminar
Time: reception at 5:30PM, seminar at 6:00PM
Title: Population genomics and adaptation in fungi
Speaker: John Taylor (University of California- Berkeley)
Location: HUCE Seminar Room 310 (24 Oxford St, 3rd Floor, Cambridge)
Host: Roberto Kolter
Contact: Nora Millan Rivas
Wednesday, October 15, 2014
4:00 PM - 5:00 PM
MOLECULAR MEDICINE SEMINAR SERIES: Shadow enhancers enable a complex transcriptional circuit in Drosophila embryos
Description: Angela DePace, Ph.D., Assistant Professor of Systems Biology, Harvard Medical School

“Shadow enhancers enable a complex transcriptional circuit in Drosophila embryos”

Room 457, New Research Building, 4th floor, Harvard Medical School, 77 Avenue Louis Pasteur
Light refreshments.
Contact: Karen Barry
Thursday, October 16, 2014
4:00 PM - 5:00 PM
Distinguished Lecture Seminar Series "Spatial neglect, the brain, and rehabilitation"
Description: A.M. Barrett, Kessler Institute for Rehabilitation and Rutgers-the State University of New Jersey
2nd floor conference room, Schepens Eye Research Institute 20 Staniford St., Boston, MA 02114
Contact: Susan Cardoza
Friday, October 17, 2014
8:30 AM - 9:30 AM
Microbial Sciences Initiative (MSI) Chalktalk: I. Castañeda
Description: Title: Mysterious branched glycerol dialkyl glycerol tetraethers (GDGTs) and their importance for paleoenvironmental reconstruction
Speaker: Isla Castañeda (UMass)
Location: HUCE Seminar Room, Room 310 (24 Oxford St, 3rd Floor, Cambridge)
Host: Roberto Kolter
Contact: Nora Millan Rivas
Monday, October 20, 2014
4:00 PM - 5:00 PM
Shared VH1-46 gene usage in pemphigus vulgaris: implications for disease development
Description: MGH/Harvard CBRC Seminar Series Guest Speaker - Aimee S. Payne, MD, PHD, Albert M. Kligman Assistant Professor of Dermatology, University of Pennsylvania
MGH East Building 149 13th Street, Isselbacher Auditorium - 7th Floor, Charlestown, MA
Registration at Lobby Security Desk Required
Contact: Vivian Theodoracopoulos
Friday, October 24, 2014
8:00 AM - 5:00 PM
The Hallmarks of Cancer Symposium
Description: For more information and registration, visit http://thehallmarksofcancer.com/ Topics :: Speakers Oncogenes :: Robert Eisenman, Fred Hutchinson Cancer Research Center Tumor Suppressor Genes :: Tyler Jacks, Koch Institute for Integrative, Cancer Research at MIT Apoptosis :: Guido Kroemer, Institut Gustave Roussy Stem Cells :: Irving Weissman, Stanford School of Medicine Invasion & Metastasis :: Robert Weinberg, Whitehead Institute, MIT Immune System :: James Allison, MD Anderson Cancer Center Tumor Microenvironment :: Johanna A. Joyce, Memorial Sloan Lettering Cancer Center Metabolism :: David Sabatini, Whitehead Institute, MIT Epigenetics :: Steve Baylin, The Johns Hopkins University School of Medicine Genomics :: Matthew Meyerson, Dana-Farber/Harvard Cancer Institute
Contact: Christine Hickey
8:30 AM - 9:30 AM
Microbial Sciences Initiative (MSI) Chalktalk: N. Joshi
Description: Title: Functional amyloid biosynthesis: A platform for materials fabrication
Speaker: Neel Joshi (SEAS)
Location: HUCE Seminar Room, Room 310 (24 Oxford St, 3rd Floor, Cambridge)
Host: Briana Burton
Contact: Nora Millan Rivas
Tuesday, October 28, 2014
9:30 AM - 1:00 PM
Next Generation Sequencing Technologies: Principles and Applications Nanocourse
Description: Lecturers
• Dr. Chad Nusbaum, Co-director, Genome Sequencing and Analysis program, Broad Institute
• Dr. Peter Park, Associate Professor of Pediatrics, Children’s Hospital, and HMS Center for Biomedical Informatics
• Mr. Robert Steen, Director, Harvard Medical School Biopolymers Facility

Traditional capillary sequencing technology using base-specific chain termination by fluorescent di-deoxy nucleotides represents modifications to the original sequencing methodology devised by Sanger and colleagues in the 1970s. Recent years have seen the development of next generation parallel sequencing technologies that are rapidly replacing older methodologies. Sequencing by synthesis enables the simultaneous sequence analysis of millions of DNA templates at the same time, or in parallel. These new approaches allow for DNA sequencing at a markedly faster pace, and often at a much cheaper price, making sequencing projects feasible for an ever-expanding number of researchers. This nanocourse will explore the methodology and principles behind parallel sequencing technology, and how it measures up to traditional sequencing methods. A discussion of the services available at the Department of Genetics Biopolymers core facility, including order placement, data output, and turnaround times, will also be included for researchers interested in utilizing these resources.

Session 1 (open to all without prior registration)
Tuesday, October 28th from 9:30am – 1:00pm
Location: The Cannon Room, Building C, Harvard Medical School

Website: https://nanosandothercourses.hms.harvard.edu/node/311
Contact: Emily Gleason
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